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Molecular Insights on Shigellosis: How the Interaction Between Invasin IpaA and Vinculin Hijacks Cellular Mechanotransduction
(2023)
With 270 million infections annually and nearly half a million death a year, shigellosis is a severe intestinal infection caused by bacteria of the Shigella family. Appearance and spread of drug-resistant strains renewed ...
Physiologically induced restructuring of focal adhesions causes mobilization of vinculin by a vesicular endocytic recycling pathway
(Elsevier Science, 2014-12)
In epithelial cells, vinculin is enriched in cell adhesion structures but is in equilibrium with a large cytosolic pool. It is accepted that when cells adhere to the extracellular matrix, a part of the soluble cytosolic ...
Mechanical Roles of Vinculin/β-catenin interaction in Adherens Junction
(2019)
Mechanical force transmission through the adherens junctions (AJs) are highly regulated processes essential for multicellular organization of tissues. AJ proteins such as E-cadherin, α-catenin, and vinculin have been shown ...
Structural characteristics of the tendinous cord-papillary muscle junction in healthy and hypertensive rats
(Pergamon-Elsevier B.V. Ltd, 2009-10-01)
Although the myotendinous junction (MTJ) of skeletal striated muscle is well known, more detailed studies regarding the structure of the cardiac MTJ are scarce. The objective of the present study was to investigate the ...
Structural characteristics of the tendinous cord-papillary muscle junction in healthy and hypertensive rats
(Pergamon-Elsevier B.V. Ltd, 2009-10-01)
Although the myotendinous junction (MTJ) of skeletal striated muscle is well known, more detailed studies regarding the structure of the cardiac MTJ are scarce. The objective of the present study was to investigate the ...
Junctional ER organization affects mechanotransduction at cadherin-mediated adhesions
(Frontiers Media, 2021)
Cadherin-mediated adhesions (also known as adherens junctions) are adhesive complexes that connect neighboring cells in a tissue. While the role of the actin cytoskeleton in withstanding tension at these sites of contact ...
Junctional ER Organization Affects Mechanotransduction at Cadherin-Mediated Adhesions
(Frontiers Media S.A., 2021)
© Copyright © 2021 Joy-Immediato, Ramirez, Cerda, Toyama, Ravasio, Kanchanawong and Bertocchi.Cadherin-mediated adhesions (also known as adherens junctions) are adhesive complexes that connect neighboring cells in a tissue. ...
Structural characteristics of the tendinous cord-papillary muscle junction in healthy and hypertensive rats
(Pergamon-Elsevier B.V. Ltd, 2014)
First body of evidence suggesting a role of a tankyrase-binding motif (TBM) of vinculin (VCL) in epithelial cells
(PeerJ Inc, 2021-05-27)
Background: Adherens junctions (AJ) are involved in cancer, infections and neurodegeneration. Still, their composition has not been completely disclosed. Poly(ADP-ribose) polymerases (PARPs) catalyze the synthesis of ...