Periodontal Debridement As A Therapeutic Approach For Severe Chronic Periodontitis: A Clinical, Microbiological And Immunological Study.

dc.creatorDel Peloso Ribeiro, Erica
dc.creatorBittencourt, Sandro
dc.creatorSallum, Enilson A
dc.creatorNociti, Francisco H
dc.creatorGonçalves, Reginaldo Bruno
dc.creatorCasati, Márcio Zaffalon
dc.date2008-Sep
dc.date2015-11-27T13:13:02Z
dc.date2015-11-27T13:13:02Z
dc.date.accessioned2018-03-29T01:07:13Z
dc.date.available2018-03-29T01:07:13Z
dc.identifierJournal Of Clinical Periodontology. v. 35, n. 9, p. 789-98, 2008-Sep.
dc.identifier1600-051X
dc.identifier10.1111/j.1600-051X.2008.01292.x
dc.identifierhttp://www.ncbi.nlm.nih.gov/pubmed/18647203
dc.identifierhttp://repositorio.unicamp.br/jspui/handle/REPOSIP/197904
dc.identifier18647203
dc.identifier.urihttp://repositorioslatinoamericanos.uchile.cl/handle/2250/1298137
dc.descriptionTo clinically, microbiologically and immunologically characterize periodontal debridement as a therapeutic approach for severe chronic periodontitis. Twenty-five patients presenting at least eight teeth with a probing pocket depth (PPD) of >or=5 mm and bleeding on probing (BOP) were selected and randomly assigned to quadrant-wise scaling and root planing or one session of full-mouth periodontal debridement. The following clinical outcomes were assessed: plaque index, BOP, position of gingival margin, relative attachment level (RAL) and PPD. Real-time PCR was used for quantitative analysis of Aggregatibacter actinomycetemcomitans, Porphyromonas gingivalis and Tannerella forsythia. The enzyme-linked immunosorbent assay permitted the detection of IL-1beta, prostaglandin E(2), INF-gamma and IL-10 in gingival crevicular fluid (GCF). All the parameters were evaluated at baseline, and at 3 and 6 months after treatment. Both the groups had similar means of PPD reduction and attachment gain over time. Besides a significant reduction in the bacterial level after treatment in both groups, microbiological analysis failed to demonstrate significant differences between them. Finally, no difference was observed between groups with respect to the levels of inflammatory mediators in GCF. Periodontal debridement resulted in a similar clinical, microbiological and immunological outcome when compared with standard scaling and root planing and therefore may be a viable approach to deal with severe chronic periodontitis.
dc.description35
dc.description789-98
dc.languageeng
dc.relationJournal Of Clinical Periodontology
dc.relationJ. Clin. Periodontol.
dc.rightsfechado
dc.rights
dc.sourcePubMed
dc.subjectAdult
dc.subjectAged
dc.subjectAggregatibacter Actinomycetemcomitans
dc.subjectBacteroides
dc.subjectChronic Periodontitis
dc.subjectColony Count, Microbial
dc.subjectDental Plaque Index
dc.subjectDental Scaling
dc.subjectDinoprostone
dc.subjectFemale
dc.subjectFollow-up Studies
dc.subjectGingival Crevicular Fluid
dc.subjectGingival Hemorrhage
dc.subjectGingival Recession
dc.subjectHumans
dc.subjectInterferon-gamma
dc.subjectInterleukin-10
dc.subjectInterleukin-1beta
dc.subjectMale
dc.subjectMiddle Aged
dc.subjectPeriodontal Attachment Loss
dc.subjectPeriodontal Pocket
dc.subjectPorphyromonas Gingivalis
dc.subjectRoot Planing
dc.subjectSingle-blind Method
dc.subjectTreatment Outcome
dc.subjectUltrasonic Therapy
dc.titlePeriodontal Debridement As A Therapeutic Approach For Severe Chronic Periodontitis: A Clinical, Microbiological And Immunological Study.
dc.typeArtículos de revistas


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