Artículos de revistas
Probing The Stereoselectivity Of The Heck Arylation Of Endocyclic Enecarbamates With Diazonium Salts. Concise Syntheses Of (2s,5r)-phenylproline Methyl Ester And Schramm's C-azanucleoside.
Registro en:
Organic Letters. v. 5, n. 3, p. 305-8, 2003-Feb.
1523-7060
10.1021/ol027268a
12556178
Autor
Severino, Elias A
Costenaro, Edson R
Garcia, Ariel L L
Correia, Carlos Roque D
Institución
Resumen
[reaction: see text] The diastereoselectivity of the Heck arylation of several chiral, nonracemic, five-membered endocyclic enecarbamates with aryldiazonium tetrafluoroborates was evaluated. The cis selectivity observed for some enecarbamates bearing coordinating groups was explored in the concise synthesis of the (2S,5R)-(+)-phenylproline methyl ester, a scaffold for the nonpeptide cholecystokinin antagonist (+)-RP 66803, and in the synthesis of Schramm's potent antiprotozoan C-azanucleoside. 5 305-8