Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq)The performance of oxygen scavengers can be influenced by several conditions, such as temperature (T) and relative humidity (RH), which are considered to be the two major factors. Therefore, the development of new scavengers requires the study of their performance, with these conditions varied. In this paper, the response surface methodology (RSM) was used to study the performance of a newly developed oxygen scavenger sachet and to model the influences of T and RH and their interaction on the absorption capacity and rate constant of the developed sachet. Commercial oxygen scavenger sachets were used for comparison purposes. The oxygen absorption capacity and rate constant were evaluated with a 22 factorial design with a central point. The results showed that each absorber sachet presented a different behaviour and there were significant interactions between T and RH; so, the RSM was the most appropriate for these studies. The developed sachet presented a better performance compared with the commercial ones at 23 degrees C and 53% RH, which represents the condition for commercialization at room temperature of foods of intermediary water activity, while in the extreme conditions (100% RH and 37 degrees C) all sachets present a similar absorption capacity. Copyright (C) 2010 John Wiley & Sons, Ltd.236351361Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq)Company DIDAI Technology LtdConselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq)