The high-field 1H NMR analysis of 3-substituted camphors with OH, OMe, SMe, NHMe, NMe2 and Me substituents at endo and exo positions, and also with an oxo substituent, is reported. The substituent-induced chemical shifts (SCS) obtained for these difunctional systems, including those from previous work on 3-halocamphors, were examined in view of multilinear correlations with steric and electronic parameters. The resultant data show a strong contribution from the electric field mechanism, principally for the protons closer to the substituent. Carbonyl group interference on the expected SCS for the α-proton is also observed, with less deshielding than those of substituted bornanes and norbornanes. © 1997 by John Wiley & Sons, Ltd.359609613Breitmaier, E., Voelter, W., (1987) Carbon-13 NMR Spectroscopy, 3rd Ed., , VCH, Weinheim and references cited thereinZurcher, R.F., (1967) Prog. Nucl. Magn. Reson. Spectrosc., 2, p. 205Abraham, R.J., Fisher, J., (1985) Magn. Reson. Chem., 23, p. 862. , and references cited thereinApSimon, J.W., Beierbeck, H., (1971) Can. J. Chem., 49, p. 1328Schneider, H.J., Buchheit, U., Becker, N., Schmidt, G., Siehl, U., (1986) J. Am. Chem. Soc., 107, p. 7027Schneider, H.J., Buchheit, U., Hoppen, V., Schmidt, G., (1989) Chem. Ber., 122, p. 321Schneider, H.J., Buchheit, U., Becker, N., Schmidt, G., Siehl, U., (1985) J. Am. Chem. Soc., 107, p. 7027Abraham, R.J., Barlow, A.P., Rowan, A.E., (1989) Magn. Reson. Chem., 27, p. 1074Basso, E.A., Kaiser, C.R., Rittner, R., Lambert, J.B., (1994) Magn. Reson. Chem., 32, p. 205Kaiser, C.R., Rittner, R., Basso, E.A., (1994) Magn. Reson. Chem., 32, p. 503Charton, M., Motoc, I., (1983) Top. Curr. Chem., 114, p. 57Charton, M., (1975) J. Am. Chem. Soc., 97, p. 1552Taft, R.W., Topsom, R.D., (1987) Prog. Phys. Org. Chem., 16, p. 1Reynolds, W.F., Gomes, A., Maron, A., MacIntyre, D.W., Tanin, A., Hamer, G.K., Peat, I.R., (1983) Can. J. Chem., 61, p. 2376Marriott, S., Topsom, R.D., (1984) J. Am. Chem. Soc., 106, p. 7Altona, C., Ippel, J.H., Hoekzema, A.J.A.W., Erkelens, C., Groesbeek, M., Donders, L.A., Chem, M.R., 27, 504, p. 1989Basso, E.A., Kaiser, C.R., Rittner, R., Lambert, J.B., (1993) J. Org. Chem., 58, p. 7865Sanders, J.K.M., Mersh, J.D., (1983) Prog. Nucl. Magn. Reson. Spectrosc., 15, p. 353Aue, W.P., Bartholdi, E., Ernst, R.R., (1976) J. Chem. Phys., 64, p. 2229Bax, A., (1983) J. Magn. Reson., 53, p. 517Scholz, D., (1983) Synthesis, p. 944Hutchinson, J.H., Money, T., (1984) Can. J. Chem., 62, p. 1899Daniel, A., Pavia, A.A., (1971) Bull. Soc. Chim. Fr., 3, p. 1060Hassner, A., Reuss, R.H., Pinnick, H.W., (1975) J. Org. Chem., 40, p. 3427