Electrochemical and electrophoretic study of Sodium Metamizole

dc.creatorBasáez, Luisa
dc.creatorPeric, Iván M.
dc.creatorJara, Paola A.
dc.creatorSoto, Cesar A.
dc.creatorContreras, David R.
dc.creatorAguirre Céspedes, Carolina
dc.creatorVanýsek, Peter
dc.date2015-11-24T19:42:57Z
dc.date2015-11-24T19:42:57Z
dc.date2008
dc.identifierJournal of the Chilean Chemical Society 53 (3)
dc.identifier0717-9707
dc.identifierhttp://repositoriodigital.ucsc.cl/handle/25022009/498
dc.descriptionArtículo de publicación ISI
dc.descriptionElectrochemical and electrophoretic behavior of sodium metamizole under conditions of variable pH has been studied. Voltammetric results indicate that sodium metamizole behaves as a quasi-reversible system over the potential window considered. These studies were complemented with capillary zone electrophoresis analysis in order to know the starting composition of solutions of sodium metamizole at different pH valúes and buffer composition. Among degradation products , the extent of the active metabolite 4-methylaminoantipyrine was found to be media dependent as well as was the appearance of different degradation products . Consequently, the extent of the oxidation process in voltammetric studies is dependent on the composition of the starting solutions. Information obtained by cyclic voltammetry and capillary zone electrophoresis has been concordant and conclusive in that both methods can be used in a qualitative study of sodium metamizole, under the experimental conditions assayed.
dc.languageen_US
dc.publisherSociedad Chilena de Química
dc.rightsAtribucion-Nocomercial-SinDerivadas 3.0 Chile
dc.rightshttp://creativecommons.org/licenses/by-nc-nd/3.0/cl/
dc.sourcehttp://goo.gl/PWyvJj
dc.subjectSodium metamizole
dc.subjectNSAID
dc.subjectDrugs
dc.subjectVoltammetry
dc.subjectElectrochemical determination
dc.subjectCapillary zone electrophoresis
dc.titleElectrochemical and electrophoretic study of Sodium Metamizole
dc.typeArtículos de revistas


Este ítem pertenece a la siguiente institución