Objective: To compare effectiveness of OxOral® versus sodium hypochlorite in Enterococcus faecalis elimination at 15 and 60 seconds. Material and methods: Material used in the study was 36 E. faecalis ATCC 29212 cultures assigned to two groups: OxOral® and 5.25% sodium hypochlorite. Both groups were in turn divided into 15 and 60 second samples. Samples were placed in peptone water, 1 mL of irrigating solution and 1 mL of strain were left to rest. 1 mL was extracted at each time, samples were seeded into blood agar for 24 hours. Mann-Whitney U test was applied. Results: With sodium hypochlorite at 15 seconds, there were three cultures with acceptable growth and six with extended growth; at 60 seconds four cultures exhibited effective result, three acceptable and one extended. With OxOral® there was extended growth in all nine cultures at both established times, significant statistical differences were found at the 60 seconds time (p < 0.01). Conclusion: E. faecalis elimination was better with sodium hypochlorite at 60 seconds.