Relationship between carbamazepine-serum level with the presence of pain and collateral effects in patients with trigeminal neuralgia at the HECMN «La Raza» from January 2003 to June 2004
Relación de los niveles séricos de la carbamazepina con la presencia del dolor y los efectos colaterales, en pacientes con neuralgia trigeminal de la consulta externa del HECMN «La Raza» de enero 2003 a junio del 2004
| dc.contributor | en-US | |
| dc.contributor | es-ES | |
| dc.creator | Palazuelos Zambrano, Consuelo María | |
| dc.creator | López Saucedo, Francisco | |
| dc.creator | Peña Torres, Leandro Miguel | |
| dc.date | 2010-06-02 | |
| dc.date.accessioned | 2018-03-16T15:56:00Z | |
| dc.date.available | 2018-03-16T15:56:00Z | |
| dc.identifier | http://ojs.unam.mx/index.php/rom/article/view/18070 | |
| dc.identifier.uri | http://repositorioslatinoamericanos.uchile.cl/handle/2250/1203718 | |
| dc.description | The relationship between the carbamazepine-serum level and the presence of pain and other collateral effects during the treatment of trigeminal neuralgia was studied. This study was prospective, descriptive, observational, longitudinal and open ended. The 23 patients used in this study had all been diagnosed with trigeminal neuralgia and were all being treated with carbamazepine. The doses of carbamazepine, the carbamazepine serum level and the collateral effects of using carbamazepine were obtained from the clinical files. The pain intensity was measured using the Analog Visual Scale (AVS), and the results were analyzed by using a descriptive statistic. The average age of the patients studied was 54 years. 74% of the patients were female and 26% were male. The most frequently affected branch of the trigeminal nerve was the mandibular branch (in 9 cases). The maxillary branch was affected in 6 cases and in 8 cases both the mandibular and the maxillary branches were affected at the same time. The doses of carbamazepine given to the patients varied between 2.06 μg and 8.78 μg. The secondary effects were nausea, dizziness, drowsiness, or a combination of these. There is no significant relationship between the carbamazepin-serum level and the presence of neuralgia in the trigeminal nerve or any secondary effects. The individual response to the carbamazepine can be attributed to several factors: age, physical activity, other illnesses, genetics, and the consumption, frequency and dose of the medicine. | en-US |
| dc.description | Se realizó un estudio de la relación de niveles séricos de carbamazepina con la presencia del dolor y los efectos colaterales en el tratamiento de la neuralgia trigeminal en un estudio prospectivo, descriptivo, observacional, longitudinal, abierto, en pacientes con diagnóstico de neuralgia trigeminal de la consulta externa del Hospital de Especialidades Centro Médico Nacional «La Raza» tratados con carbamazepina. Del expediente clínico se analizó la dosis de carbamazepina, nivel sérico de carbamazepina y efectos colaterales, la intensidad del dolor se midió de acuerdo con la escala visual análoga (EVA), los resultados fueron analizados con estadística descriptiva. Se estudiaron 23 pacientes con edad promedio de 54 años, 74% mujeres y 26% hombres, la rama del trigémino que se afectó con mayor frecuencia fue la mandibular en 9 casos, en 6 la maxilar y en 8 se observó afección de ambas ramas. Los niveles séricos de carbamazepina fluctuaron entre 2.06 μg y 8.78 μg, los efectos secundarios fueron: náuseas, mareo y somnolencia, algunos de éstos asociados. No encontramos relación entre los niveles séricos de carbamazepina, la presencia de neuralgia del trigémino y los efectos secundarios. La respuesta individual a la carbamazepina puede ser multifactorial: Edad, actividad física, padecimiento de fondo, vínculo familiar y la autoadministración del fármaco. | es-ES |
| dc.format | application/pdf | |
| dc.language | spa | |
| dc.publisher | Facultad de Odontología | es-ES |
| dc.relation | http://ojs.unam.mx/index.php/rom/article/view/18070/17196 | |
| dc.source | Revista Odontológica Mexicana; Vol 14, No 2 | es-ES |
| dc.source | 1870-199X | |
| dc.subject | en-US | |
| dc.subject | Trigeminal neuralgia; carbamazepine; carbamazepine-serum | en-US |
| dc.subject | Cirugía maxilofacial | es-ES |
| dc.subject | Neuralgia del trigémino; carbamazepina; niveles séricos | es-ES |
| dc.title | Relationship between carbamazepine-serum level with the presence of pain and collateral effects in patients with trigeminal neuralgia at the HECMN «La Raza» from January 2003 to June 2004 | en-US |
| dc.title | Relación de los niveles séricos de la carbamazepina con la presencia del dolor y los efectos colaterales, en pacientes con neuralgia trigeminal de la consulta externa del HECMN «La Raza» de enero 2003 a junio del 2004 | es-ES |
| dc.type | Artículos de revistas | |
| dc.type | Artículos de revistas |