Entendiendo que el panteón mesoamericano guarda una gran diversidad de dioses se complica por su cambio de atributos y emblemas, así como por sus nombres, una característica que sobresalta en su clasificación e inherente a la naturaleza de la cosmovisión mesoamericana es su fusión y fisión. En este artículo estos fenómenos de fusión y fisión son sugeridos como técnicas de análisis para investigar si las deidades pueden encontrarse en los patrones de asentamientos, alianzas políticas, relaciones de parentesco, clases sociales, etc. En este sentido se sugieren nuevas líneas de investigación.Understanding the ancient Mesoamerican Indigenous pantheon with its great diversity of deities, is further complicated by their change of attire and emblems, as well as their many names. However, a characteristic which stands out in their classification, and which is inherent to the nature of Mesoamerican world views, is their fusion and fission; i.e., the cases in which a group of gods is also conceived as a single divinity, and the instances where a single god can separate into different entities, distributing his attributes. We must assume that the logic of these process can aid in understanding more ample concepts, and even some types of relationships and social processes, as well as political norms in which the cult of the patron gods had an important role. in this article, these phenomena of fission and fusion are suggested as tools for analysis, inquiring whether divine identities can be found in settlement patterns, political alliances, kinship, social class, and the identification of patron gods. In this way, many possibilities for new research our outlined. Further, a critique of a study on Tlaltecuhtli-Tonatiuh is made, as a possible case of the fusion of deities.