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Platelets promote macrophage polarization toward pro-inflammatory phenotype and increase survival of septic mice
(Cell Press, 2019-07)
We investigated the contribution of human platelets to macrophage effector properties in the presence of lipopolysaccharide (LPS), as well as the beneficial effects and time frame for platelet transfusion in septic animals. ...
Biological and inflammatory effects of antigen 5 from polybia paulista (Hymenoptera, vespidae) venom in mouse intraperitoneal macrophages
(2021-12-01)
The social wasp Polybia paulista (Hymenoptera, Vespidae) is highly aggressive, being responsible for many medical occurrences. One of the most allergenic components of this venom is Antigen 5 (Poly p 5). The possible ...
MicroRNA 21 is a homeostatic regulator of macrophage polarization and prevents prostaglandin E-2-mediated M2 generation
(Public Library Science, 2015)
M1 Macrophage Polarization Is Dependent on TRPC1-Mediated Calcium Entry
(Elsevier Inc., 2018-10)
Macrophage plasticity is essential for innate immunity, but in-depth signaling mechanism(s) regulating their functional phenotypes are ill-defined. Here we report that interferon (IFN) g priming of naive macrophages induces ...
M1 macrophage polarization is dependent on TRPC1-mediated calcium entry
(Elsevier (Cell Press), 2018)
Abstract: Macrophage plasticity is essential for innate immunity, but in-depth signaling mechanism(s) regulating their functional phenotypes are ill-defined. Here we report that interferon (IFN) γ priming of naive macrophages ...
Downhill exercise-induced changes in gene expression related with macrophage polarization and myogenic cells in the triceps long head of rats
(Springer, 2015-02-01)
Macrophages are one of the most heterogenic immune cells involved in skeletal muscle regeneration. After skeletal muscle damage, M1 phenotypes exhibit pro-inflammatory reaction. in a later stage, they are converted to M2 ...
Peptides conjugated to gold nanoparticles induce macrophage activation
(2009)
Macrophages that react against pathogenic organisms can also be activated with artificial nanometric units consisting of gold nanoparticles (Au NPs) with a peptide coating. Using bone marrow-derived macrophages, here we ...