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Diaphragm muscle structure in the elderly: Findings from an autopsy study
(Elsevier B.V., 2020-02-01)
Sarcopenia is characterized as aging-related weakness and atrophy, which decreases the diaphragm force generating capacity leading to a decrease of expulsive non-ventilatory motor behaviors, which are critical for airway ...
Cigarette smoking impairs the diaphragm muscle structure of patients without respiratory pathologies: An autopsy study
(2019-01-01)
Background/Aims: Smoking is a major risk factor for several cardiovascular and pulmonary diseases, and it has also been associated with the loss of skeletal muscle mass and strength leading to sarcopenia. The aim of this ...
Evaluation of the diaphragm muscle remodeling, inflammation, oxidative stress and vascularization in smokers: An autopsy study
(2020-01-01)
Background/Aims: Cigarette smoking is a key factor in systemic inflammation and oxidative stress, and it has also been associated with the loss of muscle strength and an elevated risk of pulmonary diseases. Thus, this study ...
Neuromuscular synapse degeneration without muscle function loss in the diaphragm of a murine model for Huntington's Disease
(2018-06-01)
Huntington's disease (HD) is an autosomal dominant neurodegenerative disease characterized by chorea, incoordination and psychiatric and behavioral symptoms. The leading cause of death in HD patients is aspiration pneumonia, ...
Tempol improves redox status in mdx dystrophic diaphragm muscle
(2020-12-01)
Oxidative stress is a critical element in relationship to the pathophysiology of Duchenne muscular dystrophy (DMD). In the mice the diaphragm (DIA) is most resembles the dystrophic human pathology. In this study we have ...
Down-regulation of MyoD gene expression in rat diaphragm muscle with heart failure
(Wiley-Blackwell, 2008-06-01)
Diaphragm myopathy has been described in patients with heart failure (HF), with alterations in myosin heavy chains (MHC) expression. The pathways that regulate MHC expression during HF have not been described, and myogenic ...
Down-regulation of MyoD gene expression in rat diaphragm muscle with heart failure
(Wiley-Blackwell, 2008-06-01)
Diaphragm myopathy has been described in patients with heart failure (HF), with alterations in myosin heavy chains (MHC) expression. The pathways that regulate MHC expression during HF have not been described, and myogenic ...
Changes in types of muscle fibers induced by transcutaneous electrical stimulation of the diaphragm of rats
(Assoc Bras Divulg CientificaSao PauloBrasil, 2008)
Ultrastructural Study of the Denervated Diaphragm in Rats
(Soc Chilena Anatomia, 2013-09-01)
The structural alterations that occur in the muscle fibers of denervated rat diaphragms were studied. Fifteen adult male albino rats (Rattus norvegicus) with a mean weight of 200 g and about 60 days of age were used. ...
Effects of duodenal-jejunal bypass on structure of diaphragm in western diet obese rats
(2017-01-01)
Purpose: To evaluate the effects of duodenal-jejunal bypass (DJB) on the diaphragm muscle of obese rats fed on a western diet (WD). Methods: Eighteen male Wistar rats were fed a standard rodent chow diet (CTL group) or WD ...