Artículos de revistas
Diaphragm muscle structure in the elderly: Findings from an autopsy study
Fecha
2020-02-01Registro en:
Acta Histochemica. Munich: Elsevier Gmbh, v. 122, n. 2, 5 p., 2020.
0065-1281
10.1016/j.acthis.2019.151487
WOS:000527878000009
Autor
Universidade de São Paulo (USP)
Univ Sao Judas Tadeu
Universidade Estadual Paulista (Unesp)
Institución
Resumen
Sarcopenia is characterized as aging-related weakness and atrophy, which decreases the diaphragm force generating capacity leading to a decrease of expulsive non-ventilatory motor behaviors, which are critical for airway clearance. Thus, this study aimed to analyze the histopathology of the diaphragm in postmortem samples. Thirty individuals were included. Diaphragm samples were stained with hematoxylin and eosin for histopathological analysis. Picrosirius stain was used to highlight the collagen fibers. We observed a positive association between advancing age and histopathological findings in the diaphragm structure. We suggest that age is a key factor in increasing diaphragm muscle histopathology. However, further clinicopathological studies are needed to confirm our findings.