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Levodopa Causes Striatal Cholinergic Interneuron Burst-Pause Activity in Parkinsonian Mice
(Wiley-liss, div John Wiley & Sons Inc., 2021-07)
Background: Enhanced striatal cholinergic interneuron activity contributes to the striatal hypercholinergic state in Parkinson's disease (PD) and to levodopa-induced dyskinesia. In severe PD, dyskinesia and motor fluctuations ...
Treatment with dexamethasone alters yawning behavior induced by cholinergic but not dopaminergic agonist
(Elsevier B.V., 1999-01-15)
Because stressful manipulations have been reported to modify drug-induced yawning, the present study investigated the effects of single and repeated treatment with a synthetic glucocorticoid, dexamethasone (DEXA) on ...
Participation of the cholinergic system in the ethanol-induced suppression of paradoxical sleep in rats
(Associação Brasileira de Divulgação Científica, 2008-09-01)
Sleep disturbance is among the many consequences of ethanol abuse in both humans and rodents. Ethanol consumption can reduce REM or paradoxical sleep (PS) in humans and rats, respectively. The first aim of this study was ...
Acute effect of intracerebroventricular administration of lead on the drinking behavior of rats induced by dehydration or central cholinergic and angiotensinergic stimulation
(1994)
In the present paper, the acute effect of third ventricle injections of lead acetate (5, 10, 100, 1000 ng/rat) on the drinking behavior of adult, male, Wistar rats was investigated. Lead generates a prompt and significant ...
Role of cholinergic, opioidergic and GABAergic neurotransmission of the dorsal hippocampus in the modulation of nociception in guinea pigs
(PERGAMON-ELSEVIER SCIENCE LTD, 2008)
Aims: Several physiological, pharmacological and behavioral lines of evidence suggest that the hippocampal formation is involved in nociception. The hippocampus is also believed to play an important role in the affective ...
Pharmacotherapies for Parkinson’s disease symptoms related to cholinergic degeneration
(Informa Healthcare, 2016-10)
Introduction: Dopamine depletion is one of the most important features of Parkinson’s Disease (PD). However, insufficient response to dopaminergic replacement therapy suggests the involvement of other neurotransmitter ...
Calcitonin modifies ligand binding to muscarinic receptor in CNS membranes
(Elsevier Science, 2000-03)
Calcitonin (CT) is a peptide produced by the thyroid gland, whose best described role is to prevent bone reabsorption, though it also participates in other biological functions through both central and peripheral mechanisms. ...
Intranasal glyphosate-based herbicide administration alters the redox balance and the cholinergic system in the mouse brain
(Elsevier Science, 2020-03)
Pesticide exposure is associated with cognitive and psychomotor disorders. Glyphosate-based herbicides (GlyBH) are among the most used agrochemicals, and inhalation of GlyBH sprays may arise from frequent aerial pulverizations. ...