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Redirection of the immune response to the functional catalytic domain of cruzipain improves protective immunity against Trypanosoma cruzi infection
(Oxford University Press, 2010-12)
Despite the strong immune responses elicited after natural infection with Trypanosoma cruzi or vaccination against it, parasite survival suggests that these responses are insufficient or inherently inadequate. T. cruzi ...
Immunometabolic control of trained immunity
Innate immune cells can adopt long-term inflammatory phenotypes following brief encounters with exogenous
(microbial) or endogenous stimuli. This phenomenon is named trained immunity and can improve host defense
against ...
A review of immune transfer by the placenta
(Shannon, 2010)
Feto-maternal immune transfer occurs via both the placenta in utero and colostrum after birth. The layers between the maternal and fetal circulation systems, known as the placental barrier, regulate immune transfer to the ...
Innate and adaptive immune responses against coronavirus
Coronaviruses (CoVs) are a member of the Coronaviridae family with positive-sense single- stranded RNA. In
recent years, the CoVs have become a global problem to public health. The immune responses (innate and
adaptive ...
Recent advances in the use of Galleria mellonella model to study immune responses against human pathogens
(2018-01-01)
The use of invertebrates for in vivo studies in microbiology is well established in the scientific community. Larvae of Galleria mellonella are a widely used model for studying pathogenesis, the efficacy of new antimicrobial ...
Enhanced immunization techniques to obtain highly specific monoclonal antibodies
(2018-01-02)
Despite fast advances in genomics and proteomics, monoclonal antibodies (mAbs) are still a valuable tool for areas such as the evolution of basic research in stem cells and cancer, for immunophenotyping cell populations, ...
The neonatal immune system: immunomodulation of infections in early life
(EXPERT REVIEWSLONDON, 2012)
The innate and adaptive immune responses in neonates are usually functionally impaired when compared with their adult counterparts. The qualitative and quantitative differences in the neonatal immune response put them at ...
Immune Response Towards Snake Venoms
(2011)
The immune response involves a complex repertoire of innate and adaptive responses to foreign agents in the organism. The present review focuses on the immune response to snake venoms, including those occurring in snakebite ...
Development of Fish Immunity and the Role of β-Glucan in Immune Responses
(2020-11-17)
Administration of β-glucans through various routes, including immersion, dietary inclusion, or injection, have been found to stimulate various facets of immune responses, such as resistance to infections and resistance to ...
The role of glucose homeostasis on immune function in response to exercise: The impact of low or higher energetic conditions
(2020-04-01)
Immune cells are bioenergetically expensive during activation, which requires tightly regulated control of metabolic pathways. Both low and high glycemic conditions can modulate immune function. States of undernourishment ...