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Mostrando ítems 11-20 de 215
Regulation of hypoxia-inducible factor-1 alpha (HIF-1 alpha) expression by interleukin-1 beta (IL-1 beta), insulin-like growth factors I (IGF-I) and II (IGF-II) in human osteoarthritic chondrocytes
(Hospital Clinicas, Univ Sao PauloSao PauloBrasil, 2012)
Consecuencias Metabólicas e Inmunológicas de la Inducción de la Actividad de HIF-1α en Linfocitos T CD4+ Infectados con VIH-1
(2019-02-28)
La activación inmune crónica y la inflamación son características de la infección por VIH-1 y una de las principales causas de eventos graves no relacionados con el SIDA en personas infectadas bajo tratamiento antirretroviral ...
Hypoxia, hypoxia-inducible factor-1 alpha and vascular endothelial growth factor in a murine model of Schistosoma mansoni infection
(Academic Press Inc Elsevier ScienceSan DiegoEUA, 2010)
Elevated Glucose Levels Favor SARS-CoV-2 Infection and Monocyte Response through a HIF-1α/Glycolysis-Dependent Axis
(2020-09-01)
COVID-19 can result in severe lung injury. It remained to be determined why diabetic individuals with uncontrolled glucose levels are more prone to develop the severe form of COVID-19. The molecular mechanism underlying ...
The role of tumor hypoxia in MUC1-positive breast carcinomas
(SPRINGER, 2011)
Mucin 1 (MUC1) is a glycoprotein that is expressed on apical cell membranes in a variety of normal tissues. MUC1 is involved in cell signaling, inhibition of cell-cell and cell matrix adhesion, apoptosis, proliferation, ...
Hypoxia-Inducible Factor (HIF): Fuel for Cancer Progression
(Bentham Science Publ. LTD, 2021)
Hypoxia is an integral part of the tumor microenvironment, caused primarily due to rapidly multiplying tumor cells and a lack of proper blood supply. Among the major hypoxic pathways, HIF-1 transcription factor activation ...
HIF-1α regulates tumor progression in a human epithelial ovarian cancer model
(Fundación Revista Medicina, 2021)
Ovarian cancer is the seventh most common cancer in women and the eighth cause of cancer death. The treatment of this disease has been the same for the past decades, and the development of new drugs is needed. Hypoxia is ...
Molecular markers of angiogenesis and metastasis in lines of oral carcinoma after treatment with melatonin
(Bentham Science Publ Ltd, 2015)
The hypoxia factor Hif-1 alpha controls neural crest chemotaxis and epithelial to mesenchymal transition
(2013)
One of the most important mechanisms that promotes metastasis is the stabilization of Hif-1 (hypoxia-inducible transcription factor 1). We decided to test whether Hif-1α also was required for early embryonic development. ...