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Protective effects of etoricoxib, a selective inhibitor of cyclooxygenase-2, in experimental periodontitis in rats
(2005-06-01)
Background: The purpose of the present study was to evaluate the effect of a potent selective cyclooxygenase-2 (COX-2) inhibitor, etoricoxib, on the prevention of alveolar bone loss in experimental periodontitis induced ...
Lipoperoxidation and cyclooxygenases 1 and 2 inhibitory compounds from Iryanthera juruensis
(Amer Chemical Soc, 2007-04-04)
Plants from Iryanthera genus have been traditionally used as food supplements by South American Indians. The MeOH extract of leaves of Iryanthera juruensis, one of the plants endemic to the Amazon region and consumed in ...
Leaves of eugenia brasiliensis used as a folk medicine contain cyclooxygenase enzyme and lipid peroxidation inhibitory compounds
(2018-01-01)
Tea prepared from leaves of Eugenia brasiliensis has been used as a folk medicine in Brazil to alleviate inflammation and pain. In this study, tea and methanolic extract inhibited cyclooxygenase (COX-1 and -2) enzymes and ...
Modelagem molecular de derivados pirimidínicos e estudos de docking nas enzimas ciclooxigenase 1 e ciclooxigenase 2
(Universidade Federal de São CarlosBRUFSCarPrograma de Pós-Graduação em Biotecnologia - PPGBiotec, 2010-11-23)
In this research molecular docking was used to study enzime-ligand complexes of Cyclooxygenase 1 (COX-1) and Cyclooxygenase 2 (COX-2) with pyrimidine derivatives, aiming at understanding the possible mechanisms of action ...
Leaves of Eugenia brasiliensis Used as a Folk Medicine Contain Cyclooxygenase Enzyme and Lipid Peroxidation Inhibitory Compounds
(Natural Products Inc, 2018-08-01)
Tea prepared from leaves of Eugenia brasiliensis has been used as a folk medicine in Brazil to alleviate inflammation and pain. In this study, tea and methanolic extract inhibited cyclooxygenase (COX-1 and -2) enzymes and ...
Immunohistochemical Expression Of Cyclooxygenase-2 (cox-2) In Oral Nevi And Melanoma
(WILEY-BLACKWELLHOBOKEN, 2016)
Selective cyclooxygenase-2 inhibition protects against myocardial damage in experimental acute ischemia
(Faculdade de Medicina / USP, 2009)
BACKGROUND: Acute myocardial infarction is associated with tissue inflammation. Early coronary reperfusion clearly improves the outcome but may help propagate the inflammatory response and enhance tissue damage. Cyclooxygenase-2 ...
Effects of Bothrops asper snake venom on the expression of cyclooxygenases and production of prostaglandins by peritoneal leukocytes in vivo, and by isolated neutrophils and macrophages in vitro
(2009-03)
In this study, the ability of Bothrops asper snake venom (BaV) to increase the production of prostaglandins PGE2 and PGD2 was assessed in a mouse model in vivo and in inflammatory cells in vitro. In addition, the expressions ...
Effects of Bothrops asper snake venom on the expression of cyclooxygenases and production of prostaglandins by peritoneal leukocytes in vivo, and by isolated neutrophils and macrophages in vitro
(2009-03)
In this study, the ability of Bothrops asper snake venom (BaV) to increase the production of prostaglandins PGE2 and PGD2 was assessed in a mouse model in vivo and in inflammatory cells in vitro. In addition, the expressions ...