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Bisphosphonate-associated osteonecrosis of the jaw 2 years after teeth extractions: A case report solved with non-invasive treatment
(2014-01-01)
Bisphosphonates are a type of drugs known to inhibit bone resorption through complex interventions. Their primary mechanism of action is aimed at the cellular level, inhibiting osteoclast activity and, thus, bone resorption. ...
Care Required When Using Bisphosphonates in Dental Surgical Practice
(Lippincott Williams & Wilkins, 2013)
Management of Osteonecrosis of the Jaws in Patients With History of Bisphosphonates Therapy
(Lippincott Williams & Wilkins, 2014)
The purine transferase from Trypanosoma cruzi as a potential target for bisphosphonate-based chemotherapeutic compounds
(Pergamon-Elsevier Science Ltd, 2004-09)
We identified and tested bisphosphonates as inhibitors of a protozoan molecular target. Computational modeling studies demonstrated that these compounds are mimics of the natural substrate of the enzyme. The most potent ...
2-alkylaminoethyl-1,1-bisphosphonic acids are potent inhibitors of the enzymatic activity of Trypanosoma cruzi squalene synthase
(American Society for Microbiology, 2012-08)
As part of our efforts aimed at searching for new antiparasitic agents, the effect of representative 2-alkylaminoethyl-1,1-bisphosphonic acids on Trypanosoma cruzi squalene synthase (TcSQS) was investigated. These compounds ...
Birefringence of the Secretory-Stage Enamel Organic Extracellular Matrix from Rats Submitted to Successive Injections of Bisphosphonates
(Informa HealthcareLondonInglaterra, 2010)
Synthesis and biological evaluation of 1-alkylaminomethyl-1,1-bisphosphonic acids against Trypanosoma cruzi and Toxoplasma gondii
(Pergamon-Elsevier Science Ltd, 2019-08)
As an extension of our project aimed at the search for new chemotherapeutic agents against Chagas disease and toxoplasmosis, several 1,1-bisphosphonates were designed, synthesized and biologically evaluated against Trypanosoma ...
Biphosphonate and Jaws Osteonecrosis. Considerations About of Treatment
(Soc Chilena AnatomiaTemucoChile, 2008)
Antiresorptive drugs (bisphosphonates), atypical fractures and rebound effect: new evidence of similitude
(ELSEVIER SCI LTDOXFORD, 2012)
Background: Homeopathy is based on treatment by similitude ('like cures like') administering to sick individuals substances that cause similar symptoms in healthy individuals, employing the secondary and paradoxical action ...