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Impairment of angiogenic sphingosine kinase-1/sphingosine-1-phosphate receptors pathway in preeclampsia
(2016)
Preeclampsia (PE), is a serious pregnancy disorder characterized in the early gestation by shallow trophoblast invasion, impaired placental neo-angiogenesis, placental hypoxia and ischemia, which leads to maternal and fetal ...
Optimized protocols to analyze sphingosine 1-phosphate signal transduction pathways during acrosomal exocytosis in human sperm
(Humana Press, 2012)
Regulated secretion is a central issue for the specific function of many cells; for instance, mammalian sperm acrosomal exocytosis is essential for egg fertilization. Sphingosine 1-phosphate is a bioactive sphingolipid ...
Sphingosine kinase signalling in immune cells
(SABER ULA, 2008)
Sphingosine kinase signalling in immune cells
(SABER ULA, 2008)
Stratification of Sphingosine Kinase-1 Expression and Activity in Rat Kidney
(Karger, 2008-12)
Sphingosine-1-phosphate, the product of sphingosine kinase (SK) activity, is a sphingolipid metabolite that regulates cell growth, survival and migration. It is also known to affect diuresis, natriuresis and renovascular ...
Quantification of sphingosine-1-phosphate (S1P) in patients with periodontitis stage II grade B
(Facultad de Odontología. Universidad de Costa Rica, 2022)
Sphingolipids as emerging mediators in retina degeneration
(Frontiers Media S.A., 2019-06-11)
The sphingolipids ceramide (Cer), sphingosine-1-phosphate (S1P), sphingosine (Sph), and ceramide-1-phosphate (C1P) are key signaling molecules that regulate major cellular functions. Their roles in the retina have gained ...
Human eosinophil chemotaxis and selective in vivo recruitment by sphinglosine 1-phosphate
(Natl Acad SciencesWashingtonEUA, 2004)
Targeting defective sphingosine kinase 1 in Niemann–Pick type C disease with an activator mitigates cholesterol accumulation
(American Society for Biochemistry and Molecular Biology, 2020-07)
Niemann–Pick type C (NPC) disease is a lysosomal storage disorder arising from mutations in the cholesterol-trafficking protein NPC1 (95%) or NPC2 (5%). These mutations result in accumulation of low-density lipoprotein-derived ...