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Characterisation of pvmdr1 and pvdhfr genes associated with chemoresistance in Brazilian Plasmodium vivax isolates
(Fundação Oswaldo Cruz. Instituto Oswaldo Cruz, 2018)
Single-Nucleotide Polymorphism and Copy Number Variation of the Multidrug Resistance-1 Locus of Plasmodium vivax: Local and Global Patterns
(AMER SOC TROP MED & HYGIENEMCLEAN, 2012)
Emerging resistance to chloroquine (CQ) poses a major challenge for Plasmodium vivax malaria control, and nucleotide substitutions and copy number variation in the P. vivax multidrug resistance 1 (pvmdr-1) locus, which ...
Molecular surveillance of the Plasmodium vivax multidrug resistance 1 gene in Peru between 2006 and 2015
(BioMed Central, 2020)
Background: The high incidence of Plasmodium vivax infections associated with clinical severity and the emergence of chloroquine (CQ) resistance has posed a challenge to control efforts aimed at eliminating this disease. ...
Simultaneous detection of Plasmodium vivax dhfr, dhps, mdr1 and crt-o resistance-associated mutations in the Colombian Amazonian region
(2018)
Background: Malaria continues being a public health problem worldwide. Plasmodium vivax is the species causing the largest number of cases of malaria in Asia and South America. Due to the lack of a completely effective ...
Variação de Número de Cópias em Genes Relacionados à Resistência aos Antimaláricos em Isolados de Plasmodium spp. do Brasil
(2017)
Um dos maiores desafios do controle da malária é a
resistência do parasito aos
antimaláricos. A biologia molecular tem permitido a c
ompreensão desse fenótipo
com o estudo de marcadores associados a ela, tais c
omo o ...