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Approaches based on tree-structures classifiers to protein fold prediction
(Institute of Electrical and Electronics Engineers Inc., 2017-08)
Protein fold recognition is an important task in the biological area. Different machine learning methods such as multiclass classifiers, one-vs-all and ensemble nested dichotomies were applied to this task and, in most of ...
Analyzing the effect of homogeneous frustration in protein folding
(2013-10-01)
The energy landscape theory has been an invaluable theoretical framework in the understanding of biological processes such as protein folding, oligomerization, and functional transitions. According to the theory, the energy ...
Analyzing the effect of homogeneous frustration in protein folding
(2013-10-01)
The energy landscape theory has been an invaluable theoretical framework in the understanding of biological processes such as protein folding, oligomerization, and functional transitions. According to the theory, the energy ...
Folding kinetics of the cooperatively folded subdomain of the IκBα ankyrin repeat domain
(Academic Press Ltd - Elsevier Science Ltd, 2011-04)
The ankyrin repeat (AR) domain of IκBα consists of a cooperative folding unit of roughly four ARs (AR1-AR4) and of two weakly folded repeats (AR5 and AR6). The kinetic folding mechanism of the cooperative subdomain, IκBα ...
Detailing Protein Landscapes under Pressure
(Cell Press, 2016-12)
Natural protein molecules are remarkablephysical objects. Despite the astronomicalnumber of competing structuralforms, these systems self-organize intobeautiful structural ensembles in biologicallyshort timescales, puzzlingout ...
Specific and nonspecific collapse in protein folding funnels
(2002-04-22)
Experiments with fast folding proteins are beginning to address the relationship between collapse and folding. We investigate how different scenarios for folding can arise depending on whether the folding and collapse ...
Specific and nonspecific collapse in protein folding funnels
(2002-04-22)
Experiments with fast folding proteins are beginning to address the relationship between collapse and folding. We investigate how different scenarios for folding can arise depending on whether the folding and collapse ...