Buscar
Mostrando ítems 1-10 de 282
New perspective on the pathophysiology of panic: merging serotonin and opioids in the periaqueductal gray
(Associação Brasileira de Divulgação Científica, 2012)
Panic disorder patients are vulnerable to recurrent panic attacks. Two neurochemical hypotheses have been proposed to explain this susceptibility. The first assumes that panic patients have deficient serotonergic inhibition ...
L-Allylglycine dissociates the neural substrates of fear in the periaqueductal gray of rats
(PERGAMON-ELSEVIER SCIENCE LTD, 2010)
The dorsal (dPAG) and ventral (vPAG) regions of the periaqueductal gray are well known to contain the neural substrates of fear and anxiety. Chemical or electrical stimulation of the dPAG induces freezing, followed by a ...
Lack of effects of clomipramine on Fos and NADPH-diaphorase double-staining in the periaqueductal gray after exposure to an innate fear stimulus
(PERGAMON-ELSEVIER SCIENCE LTD, 2008)
Lack of effects of clomipramine on Fos and NADPH-diaphorase double-staining in the periaqueductal gray after exposure to an innate fear stimulus - nitric oxide (NO) acts as a neurotransmitter in the rat dorsolateral ...
Cardiovascular effects of acetylcholine microinjection into the ventrolateral and dorsal periaqueductal gray of rats
(ELSEVIER SCIENCE BV, 2011)
In the present study, we describe the cardiovascular effects of local acetylcholine (Ach) microinjection into both the ventrolateral (vlPAG) and dorsal (dPAG) periaqueductal gray areas of anesthetized rats and the possible ...
The ventrolateral periaqueductal gray is involved in the cardiovascular response evoked by L-glutamate microinjection into the lateral hypothalamus of anesthetized rats
(ELSEVIER IRELAND LTD, 2008)
Microinjection Of L-glutamate (L-glu: 1, 3, 10 and 30nmol/100nL) into the lateral hypothalamus (LH) caused dose-related depressor and bradycardiac responses. The cardiovascular response to L-glu stimulation of the LH was ...
Cardiovascular responses to noradrenaline microinjection in the ventrolateral periaqueductal gray of unanesthetized rats
(WILEY-LISS, 2008)
The periaqueductal gray area (PAG) is a mesencephalic area involved in cardiovascular modulation. Noradrenaline (NA), a neurotransmitter involved in central blood pressure control, is present in the rat PAG. We report here ...
Cardiovascular responses to glutamate microinjection in the dorsomedial periaqueductal gray of unanesthetized rats
(WILEY-BLACKWELLHOBOKEN, 2012)
The periaqueductal gray area (PAG) is a mesencephalic area involved in cardiovascular modulation. Glutamate (L-Glu) is an abundant excitatory amino acid in the central nervous system (CNS) and is present in the rat PAG. ...
Organization of electrically and chemically evoked defensive behaviors within the deeper collicular layers as compared to the periaqueductal gray matter of the rat
(Elsevier B.V., 2005-01-01)
Stimulation of the periaqueductal gray matter (PAG) and the deeper layers of superior colliculus (SC) produces both freezing (tense immobility) and flight (trotting, galloping and jumping) behaviors along With exophthalmus ...
Stimulation of 5-HT1A or 5-HT2A receptors in the ventrolateral periaqueductal gray causes anxiolytic-, but not panicolytic-like effect in rats
(ELSEVIER SCIENCE BV, 2009)
Evidences from studies using electrical or chemical stimulation of the midbrain periaqueductal gray (PAG) suggest that whereas the dorsal PAG is critical for the regulation of panic-related defensive behaviors, the ...
Involvement of the midbrain periaqueductal gray 5-HT1A receptors in social conflict induced analgesia in mice
(Elsevier B.V., 1998-03-26)
Recent results from our laboratory have shown that 30-bites social conflict in mice produces a high-intensity, short-term analgesia which is attenuated by systemically injected 5-HT1A receptor agonists, such as BAY R 1531 ...