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Functional Expression of Chemoreceptors with the Help of a Guanine Nucleotide Exchange Factor
(BLACKWELL PUBLISHING, 2009)
Odorant receptors and other chemoreceptors are usually poorly expressed in the plasma membrane of heterologous cells. A key point of regulation in G protein-mediated signaling is the interconversion between the active ...
Ric-8A, a G alpha protein guanine nucleotide exchange factor potentiates taste receptor signaling
(FRONTIERS RES FOUND, 2009)
Taste receptors for sweet, bitter and umami tastants are G-protein-coupled receptors (GPCRs). While much effort has been devoted to understanding G-protein-receptor interactions and identifying the components of the ...
Molecular basis of ligand dissociation in β-adrenergic receptors
(Public Library of Science, 2011)
The important and diverse biological functions of β-adrenergic receptors (βARs) have promoted the search for compounds to stimulate or inhibit their activity. In this regard, unraveling the molecular basis of ligand ...
Oxidative stress in atherosclerosis-prone mouse is due to low antioxidant capacity of mitochondria
(Federation Amer Soc Exp BiolBethesdaEUA, 2004)