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Prediction of non-genotoxic carcinogenicity based on genetic profiles of short term exposure assays
(Korean Society of Toxicology, 2016-06)
Non-genotoxic carcinogens are substances that induce tumorigenesis by non-mutagenic mechanisms and long term rodent bioassays are required to identify them. Recent studies have shown that transcription profiling can be ...
A review of the carcinogenic potential of glyphosate by four independent expert panels and comparison to the IARC assessment
(2016-09-30)
The International Agency for Research on Cancer (IARC) published a monograph in 2015 concluding that glyphosate is “probably carcinogenic to humans” (Group 2A) based on limited evidence in humans and sufficient evidence ...
Glyphosate rodent carcinogenicity bioassay expert panel review
(2016-09-30)
Glyphosate has been rigorously and extensively tested for carcinogenicity by administration to mice (five studies) and to rats (nine studies). Most authorities have concluded that the evidence does not indicate a cancer ...
Chronic ethanol consumption in mice does not induce DNA damage in somatic or germ cells, evaluated by the bone marrow micronucleous assay and the dominant lethal mutation assay
(2012)
Although alcohol is known to be a carcinogen for humans, ethanol-genotoxicity studies are incomplete. Ethanol seems not to be a bacterial mutagen, but the results are conflicting in rodent assays. We investigate the ...
Genotoxic effects induced by beta-myrcene following metabolism by liver HepG2/C3A human cells
(2019-02-01)
Beta-myrcene [or myrcene (1,6-Octadiene, 7-methyl-3-methylene-)] and the essential oils containing this monoterpene have been widely used in cosmetics, detergents, and soaps, and as flavoring additives for food and beverages. ...
Monitoring human genotoxicity risk associated to urban and industrial Buenos Aires air pollution exposure
(Springer Heidelberg, 2020-02-08)
The quality of life in large megacities is directly affected by its air quality. In urban environments, suspended particles from anthropogenic origin is one of the main air contaminants identified as highly genotoxic, ...