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Modulation of dopamine uptake by nitric oxide in cultured mesencephalic neurons
(ELSEVIER SCIENCE BV, 2008)
Strong evidence obtained from in vivo and ex-vivo studies suggests the existence of interaction between dopaminergic and nitrergic systems. Some of the observations suggest a possible implication of nitric oxide (NO) in ...
Cocaine Causes Apoptotic Death in Rat Mesencephalon and Striatum Primary Cultures
(Hindawi Publishing Corporation, 2015-01-01)
To study cocaine's toxic effects in vitro, we have used primary mesencephalic and striatal cultures from rat embryonic brain. Treatment with cocaine causes a dramatic increase in DNA fragmentation in both primary cultures. ...
The neuroprotective effect of dental pulp cells in models of Alzheimer`s and Parkinson`s disease
(SPRINGER WIEN, 2009)
Aim of the present study was to investigate the neuroprotective effect of dental pulp cells (DPCs) in in vitro models of Alzheimer and Parkinson disease. Primary cultures of hippocampal and ventral mesencephalic neurons ...
CRF binding protein facilitates the presence of CRF type 2 alpha receptor on the cell surface
(2016)
Corticotropin releasing factor binding protein (CRF-BP) was originally recognized as CRF sequestering protein. However, its differential subcellular localization in different brain nuclei suggests that CRF-BP may have ...
Postnatal cell proliferation in the hippocampus is modulated by dopaminergic systems in the rat : effect of perinatal asphyxia
(Universidad de Chile, 2013)
Postnatal neurogenesis has been observed in brain regions, such as dentate gyrus of the
hippocampus and subventricular zone of telencephalon. Postnatal neurogenesis is an active
phenomenon modulated by several factors ...
Aminochrome induces microglia and astrocyte activation
(Elsevier, 2017)
Aminochrome has been suggested as a more physiological preclinical model capable of inducing five of the six mechanisms of Parkinson's Disease (PD). Until now, there is no evidence that aminochrome induces glial activation ...
In situ hybridization of chemotactically bioactive molecules on whole mounted chick embryo
(Maney Publishing, 2012-05)
In vitro assays showed that the morphogen, sonic hedgehog (Shh), the chemokine, stromal cell-derived factor-1 (SDF-1), and the growth factor, neurotrophin-3 (NT-3), behaved as chemotactic signals for neural crest cells ...
Intracellular magnesium-dependent modulation of gap junction channels formed by neuronal connexin36
(2013)
Gap junction (GJ) channels composed of Connexin36 (Cx36) are widely expressed in the mammalian CNS and form electrical synapses between neurons. Here we describe a novel modulatory mechanism of Cx36 GJ channels dependent ...