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P-Glycoprotein contributes to cell membrane depolarization of hippocampus and neocortex in a model of repetitive seizures induced by pentylenetetrazole in rats
(Bentham Science Publishers, 2013-03)
P-glycoprotein (P-gp) has been associated with pharmacoresistance and mechanisms regulating the membrane potential. However, at present it is unknown if P-gp overexpression in brain is associated with changes in membrane ...
Excitation-metabolism coupling: role of membrane depolarization on the mitochondrial function
(2016)
Depolarizing stimuli induce signaling pathways in muscle that have pleiotropic effects. Two new voltage-dependent phenomena, excitation-transcription and excitation-metabolism coupling (EMC), add to the canonical ...
Carotid body type-I cells under chronic sustained hypoxia: Focus on metabolism and membrane excitability
(Frontiers Media S.A., 2018)
Mitochondrial calcium increase induced by ryr1 and ip3r channel activation after membrane depolarization regulates skeletal muscle metabolism
(2018)
Aim: We hypothesize that both type-1 ryanodine receptor (RyR1) and IP3-receptor (IP3R) calcium channels are necessary for the mitochondrial Ca2+ increase caused by membrane depolarization induced by potassium (or by ...
Membrane depolarization induces calcium-dependent upregulation of Hsp70 and Hmox-1 in skeletal muscle cells
(2009)
Heat shock proteins (HSPs) are a conserved family of cytoprotective polypeptides, synthesized by cells in response to stress. Hsp70 and heme oxygenase 1 (Hmox-1) are induced by a variety of cellular stressors in skeletal ...
Electric field stimulation of cardiac myocytes during postnatal development
(Ieee-inst Electrical Electronics Engineers IncNew YorkEUA, 2001)
Altered ROS production, NF-κB activation and interleukin-6 gene expression induced by electrical stimulation in dystrophic mdx skeletal muscle cells
(Elsevier, 2015)
© 2015 . Duchenne muscular dystrophy is a fatal X-linked genetic disease, caused by mutations in the dystrophin gene, which cause functional loss of this protein. This pathology is associated with an increased production ...