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Phosphatidylserine lipids and membrane order precisely regulate the activity of Polybia-MP1 peptide
(2017-06-01)
Polybia-MP1 (IDWKKLLDAAKQIL-NH2) is a lytic peptide from the Brazilian wasp venom with known anti-cancer properties. Previous evidence indicates that phosphatidylserine (PS) lipids are relevant for the lytic activity of ...
Antibody-induced acetylcholine receptor clusters inhabit liquid-ordered and liquid-disordered domains
(Elsevier, 2013-10)
The distribution of nicotinic acetylcholine receptor (AChR) clusters at the cell membrane was studied in CHO-K1/A5 cells using fluorescence microscopy. Di-4-ANEPPDHQ, a fluorescent probe that differentiates between ...
Thermodynamics, transition dynamics, and texturing in polymer-dispersed liquid crystals with mesogens exhibiting a direct isotropic/smectic-A transition
(American Chemical Society, 2009-12-23)
Experimental and modeling/simulation studies of phase equilibrium and growth morphologies of novel polymer-dispersed liquid crystal (PDLC) mixtures of PS (polystyrene) and liquid crystals that exhibit a direct isotropic/smectic-A ...
Antibody-induced acetylcholine receptor clusters inhabit liquid-ordered and liquid-disordered domains
(Elsevier B.V., 2013)
Abstract: The distribution of nicotinic acetylcholine receptor (AChR) clusters at the cell membrane was studied in CHO-K1/A5 cells using fluorescence microscopy. Di-4-ANEPPDHQ, a fluorescent probe that differentiates between ...
Liquid Crystalline Nanostructured Polymer Blends
(2015-09-23)
Polymeric materials presenting liquid crystalline domains are attracting increasing attention from academia and industry due to their unique properties, particularly for optical applications and as components of high-strength ...
Psychosine remodels model lipid membranes at neutral pH
(Elsevier Science, 2018-12)
β-Galactosylsphingosine or psychosine (PSY) is a single chain sphingolipid with a cationic group, which is degraded in the lysosome lumen by β-galactosylceramidase during sphingolipid biosynthesis. A deficiency of this ...
Measuring molecular order for lipid membrane phase studies: Linear relationship between Laurdan generalized polarization and deuterium NMR order parameter
(Elsevier Science, 2019-12)
Two dimensional phase separation in lipid membranes and cell membranes is of interest to biology because of the idea of membrane rafts — compositionally heterogeneous liquid crystal domains with cellular functions. Few ...
Crossregulation between the insertion of Hexadecylphosphocholine (miltefosine) into lipid membranes and their rheology and lateral structure
(Elsevier Science, 2017-10)
Hexadecylphosphocholine (HePC, miltefosine) is an alkylphospholipid used clinically for the topical treatment of cancer and against leishmaniasis. The mechanism of action of HePC, not yet elucidated, involves its insertion ...
Lipid domains in giant unilamellar vesicles and their correspondence with equilibrium thermodynamic phases: A quantitative fluorescence microscopy imaging approach
(2009)
We report a novel analytical procedure to measure the surface areas of coexisting lipid domains in giant unilamellar vesicles (GUVs) based on image processing of 3D fluorescence microscopy data. The procedure involves the ...