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Late-Stage Fluorination of Bioactive Molecules and Biologically-Relevant Substrates
(Elsevier, 2018)
Late Stage Fluorination of Bioactive Molecules and Biologically-Relevant Substrates reviews how the use of these techniques on compounds with already known and relevant biological activity can provide new pharmaceutical ...
Fluorination methods in drug discovery
(Royal Society Of Chemistry, 2016-05)
Fluorination reactions of medicinal and biologically-active compounds will be discussed. Late stage fluorination strategies of medicinal targets have recently attracted considerable attention on account of the influence ...
Difluoromethylation Reactions of Organic Compounds
(Wiley VCH Verlag, 2017-10)
The relevance of the ‐CF2H moiety has attracted considerable attention from organic synthetic and medicinal chemistry communities, because this group can act as a more lipophilic isostere of the carbinol, thiol, hydroxamic ...
Topaz magmatic crystallization in rhyolites of the Central Andes (Chivinar volcanic complex, NW Argentina): Constraints from texture, mineralogy and rock chemistry
(Elsevier Science, 2013-10)
Topaz-bearing rhyolite lavas were erupted as domes and cryptodomes during the early history of the Late Miocene Chivinar volcano, in Central Andes. These are the only topaz rhyolite lavas recognized in Central Andes. ...
Sn-polymetallic greisen-type deposits associated with late-stage rapakivi granites, Brazil: fluid inclusion and stable isotope characteristics
(Elsevier B.V., 2005-03-01)
Tin-polymetallic greisen-type deposits in the Itu Rapakivi Province and Rondonia Tin Province, Brazil are associated with late-stage rapakivi fluorine-rich peraluminous alkali-feldspar granites. These granites contain topaz ...
Sn-polymetallic greisen-type deposits associated with late-stage rapakivi granites, Brazil: fluid inclusion and stable isotope characteristics
(Elsevier B.V., 2005-03-01)
Tin-polymetallic greisen-type deposits in the Itu Rapakivi Province and Rondonia Tin Province, Brazil are associated with late-stage rapakivi fluorine-rich peraluminous alkali-feldspar granites. These granites contain topaz ...
Late-stage electron-catalyzed perfluoroalkylation of coumarin derivatives—Thermal fluoroalkyl radical production from sodium perfluoroalkyl sulfinate salts
(Elsevier Science Sa, 2017-05)
Novel and high-yielding protocols for the late-stage synthesis of 3-perfluoroalkyl-substituted coumarin derivatives employing either perfluoroalkyl iodides RFI or sodium perfluoroalkylsulfinate salts NaSO2RF as perfluoroalkyl ...
PET/CT com 18F-FDG no planejamento radioterápico dos pacientescom carcinoma pulmonar não pequenas células: proposta de Threshold individualizado
(Universidade Federal de Minas GeraisUFMG, 2014-09-30)
Introduction: Lung carcinoma has significant relevance in the global and national epidemiological profile due to its high incidence and high mortality rate. The most common histological type is non-small cell lung carcinoma ...
New visible light organo(metal)-photocatalyzed fluoroalkylsulfanylation (RFS-) and fluoroalkylselenolation (RFSe-) reactions of organic substrates
(Elsevier Science SA, 2020-12)
The fluoroalkylsulfanyl (RFS-) and fluoroalkylselenolyl (RFSe-) groups are becoming increasingly ubiquitous moieties in synthetic organic transformations on account of their relevance in areas ranging from medicinal chemistry ...