info:eu-repo/semantics/publishedVersion
Late-Stage Fluorination of Bioactive Molecules and Biologically-Relevant Substrates
Fecha
2018Registro en:
Postigo, Jose Alberto; Late-Stage Fluorination of Bioactive Molecules and Biologically-Relevant Substrates; Elsevier; 1; 2018; 392
9780128129586
CONICET Digital
CONICET
Autor
Postigo, Jose Alberto
Resumen
Late Stage Fluorination of Bioactive Molecules and Biologically-Relevant Substrates reviews how the use of these techniques on compounds with already known and relevant biological activity can provide new pharmaceutical leads with improved medicinal properties. The fluorination strategies discussed take into account both conventional and novel reagents, including nucleophilic, electrophilic, those of a radical nature, and diverse families of organic compounds, such as (hetero) aromatic rings and aliphatic substrates. Drawing on the author's expert knowledge, this book provides researchers with a broad set of applicable methods to use in their work.Key FeaturesHighlights the latest developments in the field in a concise volumeProvides details of key fluorinating reagents across diverse families of organic compoundsExplores the current applications and future potential of fluorine in drug development.