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Construção de um vetor para recombinação de integrases do HIV-1
(Fiocruz/Instituto de Tecnologia em Imunobiológicos, 2018)
HIV-1 resistance patterns to integrase inhibitors in Chilean patients with virological failure on raltegravir-containing regimens
(Mediscript, 2020)
In this viewpoint we would like to describe our results in terms of resistance pattern in Chilean patients with virological failure (VF) on raltegravir (RAL)-containing-regimens and highlight the need for the concomitant ...
Inibidores da HIV-integrase: Potencial abordagem farmacológica para tratamento da AIDS
(2006-06-23)
AIDS has the HIV as its etiological agent. Researches has been done to find new pharmacological agents to be used in therapy, because of problems of resistance and side effects. The HIV-integrase inhibitors are some of ...
Inibidores da HIV-integrase: Potencial abordagem farmacológica para tratamento da AIDS
(2006-06-23)
AIDS has the HIV as its etiological agent. Researches has been done to find new pharmacological agents to be used in therapy, because of problems of resistance and side effects. The HIV-integrase inhibitors are some of ...
Characterization of the long-terminal repeat single-strand tail-binding site of Moloney-MuLV integrase by crosslinking
(Sociedad de Biología de Chile, 2008)
Role of the 207–218 peptide region of Moloney murine leukemia virus integrase in enzyme catalysis
(ELSEVIER, 2010)
X-ray diffraction data on a few retroviral integrases show a flexible loop near the active site. By sequence
alignment, the peptide region 207–218 of Mo-MLV IN appears to correspond to this flexible loop. In this
study, ...
Role of the 207-218 peptide region of Moloney murine leukemia virus integrase in enzyme catalysis
(2010)
X-ray diffraction data on a few retroviral integrases show a flexible loop near the active site. By sequence alignment, the peptide region 207-218 of Mo-MLV IN appears to correspond to this flexible loop. In this study, ...