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HNSCC subverts PBMCs to secrete soluble products that promote tumor cell proliferation
(Impact Journals Llc, 2017-09-05)
The immune system detects shifts from homeostasis and eliminates altered cells. However, neoplastic cells can modulate the host response to escape immunosurveillance thereby allowing tumor progression. Head and neck squamous ...
Evaluation of the methylation profile of exfoliated cell samples from patients with head and neck squamous cell carcinoma
(Wiley-Blackwell, 2014-05-01)
BackgroundSilencing of tumor suppressor genes plays a vital role in head and neck carcinogenesis. the purposes of this study were to determine the methylation profile of exfoliated tumors cells collected from patients with ...
Squamous cell carcinoma antigen as a prognostic marker and its correlation with clinicopathological features in head and neck squamous cell carcinoma: Systematic review and meta-analysis
(2018-01-01)
Background: Several studies investigate the prognostic value of squamous cell carcinoma antigen (SCC-Ag) in head and neck squamous cell carcinoma (HNSCC) patients, with contradicting findings. Considering this, the aim of ...
Galanin mediates tumor-induced immunosuppression in head and neck squamous cell carcinoma
(2022-01-01)
Purpose: Galanin receptor 2 (GALR2) plays a significant role in the progression of head and neck squamous cell carcinomas (HNSCC). Since there is virtually no information on immunomodulation mediated by its ligand in the ...
The role of T-cells in head and neck squamous cell carcinoma: From immunity to immunotherapy.
(Frontiers Research Foundation, 2023)
CYP1A2*1C, CYP2E1*5B, and GSTM1 polymorphisms are predictors of risk and poor outcome in head and neck squamous cell carcinoma patients
(Elsevier B.V., 2009-09-01)
Head and neck squamous cell carcinoma (HNSCC) is associated with environmental factors, especially tobacco and alcohol consumption. Most of the carcinogens present in tobacco smoke are converted into DNA-reactive metabolites ...
Infiltrating CD57+ inflammatory cells in head and neck squamous cell carcinoma: clinicopathological analysis and prognostic significance
(Lippincott Williams & Wilkins, 2014)
An in vitro study showing the three-dimensional microenvironment influence over the behavior of head and neck squamous cell carcinoma
(MEDICINA ORAL S LVALENCIA, 2013-08-02)
Objectives: The Head and Neck Squamous Cell Carcinoma (HNSCC) ranks sixth worldwide. The mechanisms of growth, invasion and metastasis of this pathology are extensively studied and generally related to specific variations ...