Buscar
Mostrando ítems 1-10 de 25
Cholinesterase inhibitors for Alzheimer's disease: Multitargeting strategy based on anti-Alzheimer's drugs repositioning
(Bentham Science Publishers, 2019)
Amaryllidaceae del Tolima: importancia para el tratamiento de la enfermedad de Alzheimer
(Ediciones Unibagu?, 2021)
Benzodiazepines and Related Drugs as a Risk Factor in Alzheimer's Disease Dementia
(Frontiers Media S.A., 2020)
Estudos de modelagem molecular dos mecanismos de afinidade relativa para quatro galantamínicos com potencial anti-Alzheimer
(Universidade Federal de Minas GeraisUFMG, 2017-07-17)
Alzheimer's disease is currently a serious public health and economic problem stemming from the increased life expectancy of the world's population, which results in complicated psychological symptoms in people with this ...
El género Phaedranassa (Amaryllidaceae) como fuente promisoria de metabolitos bioactivos ante la enfermedad de Alzheimer - Revisión Bibliográfica
(Universidad de Cuenca, 2022-07-22)
Amaryllidaceae family comprises a group of plant genders distributed worldwide, developing
in tropical and subtropical habitats., 33 species of plants from this family grow in Ecuador, of
which 12 are endemic. The genus ...
Arylaminopropanone Derivatives as Potential Cholinesterase Inhibitors: Synthesis, Docking Study and Biological Evaluation
(Molecular Diversity Preservation International, 2020-04)
Neurodegenerative diseases in which the decrease of the acetylcholine is observed are growing worldwide. In the present study, a series of new arylaminopropanone derivatives with N-phenylcarbamate moiety (1-16) were prepared ...
Aporphinoid Alkaloids Derivatives as Selective Cholinesterases Inhibitors: Biological Evaluation and Docking Study
(Wiley VCH Verlag, 2020-11)
Alzheimer's dementia is a neurodegenerative disease that affects the elderly population and causes memory impairment and cognitive deficit. Manifestation of this disease is associated to acetylcholine decrease; thus, ...
Aporphinoid Akaloids Derivatives as Selective Cholinesterases Inhibitors: Biological Evaluation and Docking Study
(Wiley-VCH Verlag GmbH & Co, 2020-02-11)
Alzheimer´s dementia is a neurodegenerative disease that affects the elderly population and causes memory impairment and cognitive deficit. Manifestation ofthis disease is associated to acetylcholine decrease; thus, ...
Design, facile synthesis, and evaluation of novel spiro- and pyrazolo [1,5-c]quinazolines as cholinesterase inhibitors: Molecular docking and MM/GBSA studies
(2018)
Given the wide spectrum of biological uses of pyrazolo[l,5-c]quinazoline and spiro-quinazoline derivatives as anticancer, anti-inflammatory analgesic agents, and their therapeutic applications in neurodegenerative disorders, ...
Synthesis, biological evaluation and molecular modeling studies of substitutedN-benzyl-2-phenylethanamines as cholinesterase inhibitors
(Royal Society of Chemistry, 2020-06)
In this work, we report the synthesis of a series of derivatives of N-benzyl-2-phenylethanamine which is the framework of norbelladine, the natural common precursor of the Amaryllidaceae alkaloids. These compounds were ...