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First-line endocrine therapy for advanced breast cancer. A real-world study at a Latin American university health institution
(TAYLOR & FRANCIS LTD, 2020)
Objective: Clinical guidelines recommend the use of endocrine therapy (ET) in advanced hormone receptor positive (HR+) human epidermal growth factor receptor type 2 negative (HER2-) breast cancer (BC) patients in the absence ...
Endocrine disruptors from the environment affecting breast cancer (Review)
(Spandidos, 2020)
Evaluation of carcinogenic substances from the environment is a challenge for scientists. Recently, a novel approach based on 10 key characteristics of human carcinogens classified by the International Agency for Research ...
Microenvironment and endocrine resistance in breast cancer: Friend or foe?
(Baishideng Publishing Group, 2015-12)
Breast cancer affects one in eight women around the world. Seventy five percent of these patients have tumors that are estrogen receptor positive and as a consequence receive endocrine therapy. However, about one third ...
Pesticide chlorpyrifos acts as an endocrine disruptor in adult rats causing changes in mammary gland and hormonal balance
(Pergamon-Elsevier Science Ltd, 2016-02)
Endocrine disruptors (EDs) are compounds that interfere with hormone regulation and influence mammary carcinogenesis. We have previously demonstrated that the pesticide chlorpyrifos (CPF) acts as an ED in vitro, since it ...
Nuclear action of FGF members in endocrine-related tissues and cancer: interplay with steroid receptor pathways
(Elsevier Science Inc, 2019-09)
Dysregulation of the fibroblast growth factors/fibroblast growth factor receptor (FGF/FGFR) pathway has been implicated in a wide range of human disorders and several members have been localized in the nuclear compartment. ...
Male Breast Cancer.
(2011)
Multidisciplinary Approach To Neoadjuvant Endocrine Therapy In Breast Cancer: A Comprehensive ReviewAbordagem Multidisciplinar Em Hormonioterapia Neoadjuvante No Câncer De Mama: Uma Revisão
(Federação Brasileira das Sociedades de Ginecologia e Obstetrícia, 2016)
Multidisciplinary Approach To Neoadjuvant Endocrine Therapy In Breast Cancer: A Comprehensive ReviewAbordagem Multidisciplinar Em Hormonioterapia Neoadjuvante No Câncer De Mama: Uma Revisão
(Federacao Brasileira das Sociedades de Ginecologia e Obstetricia, 2016)
Preclinical modeling of combined phosphatidylinositol-3-kinase inhibition with endocrine therapy for estrogen receptor-positive breast cancer
(2011)
Abstract
Introduction
Inhibition of phosphatidylinositol-3-kinase (PI3K) induces apoptosis when combined with estrogen deprivation in estrogen receptor (ER)-positive breast ...
Stromal-epithelial interactions and tamoxifen resistanceInteracciones estroma-epitelial al tamoxifeno
(Medicina (Buenos Aires), 2007-12)
Tamoxifen, a selective estrogen receptor modulator, is the standard endocrine treatment for hormone receptor positive breast cancer, both in the initial adjuvant therapy and as treatment of patients with metastatic disease. ...