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Binder-free twin-screw melt granulation: An effective approach to manufacture high-dose API formulations
(Elsevier Science, 2021-09-05)
This study investigates the use of twin-screw binder-free melt granulation (BFMG) in the development of high- dose solid dose formulations for low melting point thermally stable drugs. Both ibuprofen and guaifenesin are ...
A new approach to the granulation of beta-cyclodextrin inclusion complexes
(Elsevier B.V. Sa, 2010-11-01)
Cyclodextrins (CDs) are annular oligosaccharides containing 6-12 glucose unities joined together by alpha-1,4 bonds. They have a conical-truncated shape with a lipophilic cavity in which different molecules can be included ...
Influência das propriedades de granulados de celulose nas características físicas dos comprimidos
(2008-10-28)
The compaction behavior of powdered solids can be strongly influenced by the physicochemical properties of excipients because they are frequently present in the tablet in larger amounts than the drug itself. The aim of ...
Influência das propriedades de granulados de celulose nas características físicas dos comprimidos
(2008-10-28)
The compaction behavior of powdered solids can be strongly influenced by the physicochemical properties of excipients because they are frequently present in the tablet in larger amounts than the drug itself. The aim of ...
Using Fluid Bed Granulation to Improve the Dissolution of Poorly Water-Soluble Drugs
(INST TECNOLOGIA PARANACURITIBA-PARANA, 2012)
In this study, fluid bed granulation was applied to improve the dissolution of nimodipine and spironolactone, two very poorly water-soluble drugs. Granules were obtained with different amounts of sodium dodecyl sulfate and ...
Using fluid bed granulation to improve the dissolution of poorly water-soluble drugs
(Brazilian Archives of Biology and Technology, 2012)
In this study, fluid bed granulation was applied to improve the dissolution of nimodipine and spironolactone, two very poorly water-soluble drugs. Granules were obtained with different amounts of sodium dodecyl sulfate and ...
CELULOSE FIBROSA DO BAGACO DA CANA-DE-ACUCAR - AVALIACAO DA ACAO AGLUTINANTE/DESAGREGANTE EM COMPRIMIDOS CONTENDO FARMACO HIDROSSOLUVEL
(1993-12-01)
In this work, a fibrous cellulose obtained from the sugar cane bagasse was analysed about its binder/disintegrating action and about its interference degree in the dissolution rate ('in vitro') of active principles, when ...
CELULOSE FIBROSA DO BAGACO DA CANA-DE-ACUCAR - AVALIACAO DA ACAO AGLUTINANTE/DESAGREGANTE EM COMPRIMIDOS CONTENDO FARMACO HIDROSSOLUVEL
(1993-12-01)
In this work, a fibrous cellulose obtained from the sugar cane bagasse was analysed about its binder/disintegrating action and about its interference degree in the dissolution rate ('in vitro') of active principles, when ...
Influence of irrigation and intracanal dressing on the healing process of dogs' teeth with apical periodontitis.
(Munksgaard Int Publ Ltd, 1992-12-01)
Dogs' teeth with apical periodontitis were treated endodontically, Dakin's solution being used in an experimental group as the irrigation solution, and camphorated paramonochlorophenol as an intracanal dressing. For a ...