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Silencing of LRRC49 and THAP10 genes by bidirectional promoter hypermethylation is a frequent event in breast cancer
(PROFESSOR D A SPANDIDOS, 2008)
Previously we found that levels of LRRC49 (leucine rich repeat containing 49; FLJ20156) transcripts were elevated in ER-positive breast tumors compared with ER-negative breast tumors. The LRRC49 gene is located on chromosome ...
Transcriptional regulation of bidirectional gene pairs by 17-β-estradiol in MCF-7 breast cancer cells
(Associação Brasileira de Divulgação Científica, 2011)
Using cDNA microarray analysis, we previously identified a set of differentially expressed genes in primary breast tumors based on the status of estrogen and progesterone receptors. In the present study, we performed an ...
The chromatin structure of the lysozyme GAS41 origin of DNA replication changes during the cell cycle
(Sociedad de Biología de Chile, 2007)
Renaissance of Allostery to Disrupt Protein Kinase Interactions
(Elsevier Science London, 2019-11)
Protein–protein interactions often regulate the activity of protein kinases by allosterically modulating the conformation of the ATP-binding site. Bidirectional allostery implies that reverse modulation (i.e., from the ...
A small intergenic region drives exclusive tissue-specific expression of the adjacent genes in Arabidopsis thaliana
(BioMed Central, 2009-12)
Transcription initiation by RNA polymerase II is unidirectional from most genes. In plants, divergent genes, defined as non-overlapping genes organized head-to-head, are highly represented in the Arabidopsis genome. ...
The degree of enhancer or promoter activity is reflected by the levels and directionality of eRNA transcription
(Cold Spring Harbor Laboratory Press, 2018-01)
Gene expression is regulated by promoters, which initiate transcription, and enhancers, which control their temporal and spatial activity. However, the discovery that mammalian enhancers also initiate transcription questions ...
Elaboração de diretrizes para formatação de um sistema integrado de gestão de normas educacionais para o estado do Rio de Janeiro
(Universidade Federal de Juiz de ForaBrasilFaculdade de EducaçãoMestrado em Gestão e Avaliação em Educação PúblicaUFJF, 2016)
Elaboración de una biblioteca de comunicación en tiempo real entre dispositivos Smart TV LG WebOS y Android para el desarrollo de un videojuego retro
(Universidad Peruana de Ciencias Aplicadas (UPC)PE, 2020-11-25)
La industria de los dispositivos inteligentes ha crecido en los últimos años, por lo que una gran mayoría de personas cuentan con un Smart TV y al menos un teléfono inteligente en sus hogares. La transformación de la era ...