A new diterpenoid, azorellanol (5), was isolated from the whole plant of Azorella compacta (Umbelliferae). The stricture was established by using mainly one- and two-dimensional NMR techniques, whereas the absolute ...

In addition to azorellanol a new diterpenoid 7-deacetylazorellanol, has been isolated from the aerial parts oiLaretia acaulis (Cav.) Gill et Hook (Umbelliferae). Its structure was based on spectroscopic comparison with ...

Diterpenoids with trichomonicidal activity were isolated from the aerial parts of Azorella yareta Hauman. One was 13β-hydroxyazorellane, together with the known constituents mulinolic acid, mulin-11,13-dien-20-oic acid, ...

Aqueous or ethanol infusions of Azorella compacta (llareta) in common with many other plants have been used as antidiabetic in the popular medicine in the altiplanic region of Chile. In order to determine if the diterpenic ...

Azorella compacta, Azorella yareta and Laretia acaulis (Apiaceae) are native species from the high Andes Mountains, northeastern Chile, and they have being traditionally used to treat asthma, colds and bronchitis, illnesses ...

Transcription factor NF-κB plays a key role in the inducible expression of genes mediating proinflammatory effects, and is thus an important target for the development of antiinflammatory drugs. Laretia acaulis (Cav.) Gill ...

The absolute configuration of the diterpenoid 9,12-cyclomulin-13-ol (1), a constituent of Azorella and Laretia species, has been established by vibrational circular dichroism spectroscopy in combination with density ...

Four new mulinane-type diterpenoids besides the known compounds mulin-11,13-dien-20-oic acid, 13α-hydroxyazorellane, 13β- hydroxyazorellane, mulinolic acid, azorellanol, and mulin-11,13-dien-18-acetoxy- 16,20-dioic acid ...

The antituberculosis activity of 14 natural azorellane and mulinane diterpenoids isolated from Azorella compacta, Azorella madreporica, Mulinum crassifolium, and Laretia acaulis, together with eight semisynthetic ...