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Physical resistance training-induced changes in lipids metabolism pathways and apoptosis in prostate
(2020-01-29)
Background: Altered lipid metabolism is an important characteristic of neoplastic cells, with androgens and growth factors being major regulatory agents of the lipid metabolism process. We investigated the effect of physical ...
High passage numbers induce resistance to apoptosis in C2C12 muscle cells
(Sociedad Latinoamericana de Microscopía Electrónica, 2013-01)
Cell lines with high passage numbers exhibit alterations in cell Morphology and functions. In the present work, C2C12 skeletal muscle cells with either low (<20) or high (>60) passage numbers (identified as l-C2C12 or ...
Anticancer and apoptosis-inducing activities of microbial metabolites
(Pontificia Universidad Católica de Valparaíso, 2010)
Sustained activation of p53 in confluent nucleotide excision repair-deficient cells resistant to ultraviolet-induced apoptosis
(ELSEVIER SCIENCE BV, 2008)
p53 activation is one of the main signals after DNA damage, controlling cell cycle arrest, DNA repair and apoptosis. We have previously shown that confluent nucleotide excision repair (NER)-deficient cells are more resistant ...
Ha-Ras sensitizes transformed mouse skin cells to Anisomycin-induced apoptosis
(ELSEVIER SCIENCE BV, 2005-11-21)
Efforts have been made to develop a chemoprevention that selectively triggers apoptosis in malignant cancer cells. Here, we demonstrated that a mutated Ha-Ras activity is required in Anisomycin-induced apoptosis in transformed ...
Resistance to ultraviolet-induced apoptosis in DNA repair deficient growth arrested human fibroblasts is not related to recovery from RNA transcription blockage
(ELSEVIER SCIENCE BV, 2008)
The impact of ultraviolet (UV-C) photoproducts on apoptosis induction was investigated in growth arrested (confluent) and proliferating human primary fibroblasts. Confluent fibroblasts were more resistant to UV-C-induced ...
Expression of multidrug resistance proteins in prostate cancer is related with cell sensitivity to chemotherapeutic drugs
(2009)
BACKGROUND. Multidrug resistance (MDR) proteins have been associated with the lack of chemotherapy response. Expression of these proteins has been described in the prostate, but there is no information about their role in ...
Arginylated Calreticulin Increases Apoptotic Response Induced by Bortezomib in Glioma Cells
(Humana Press, 2019-03)
After retrotranslocation from the endoplasmic reticulum to the cytoplasm, calreticulin is modified by the enzyme arginyltransferase-1 (ATE1). Cellular levels of arginylated calreticulin (R-CRT) are regulated in part by the ...
Participation of the mitochondrial permeability transition pore in nitric oxide-induced plant cell death
(Elsevier Science BvAmsterdamHolanda, 2002)