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Heparins and heparinoids: Occurrence, structure and mechanism of antithrombotic and hemorrhagic activities
(Bentham Science Publ Ltd, 2004-01-01)
The correlation between structure, anticloting, antithrombotic and hemorrhagic activities of heparin, heparan sulfate, low molecular weight heparins and heparin-like compounds from various sources that are in used in ...
Development of new heparin-like compounds and other antithrombotic drugs and their interaction with vascular endothelial cells
(Associação Brasileira de Divulgação Científica, 2001-06-01)
The anticlotting and antithrombotic activities of heparin, heparan sulfate, low molecular weight heparins, heparin and heparin-like compounds from various sources used in clinical practice or under development are briefly ...
Potential antithrombotic activity detected in amaranth proteins and its hydrolysates
(Elsevier Science, 2014-07)
Amaranth protein isolate and fractions were obtained and subjected to proteolysis in order to evaluate its potential antithrombotic activity. The proteins were first hydrolyzed with alcalase (pH 10, 37 °C) and then with ...
Antithrombotic Effects of Amaranthus hypochondriacus Proteins in Rats
(Springer, 2016-03)
Cardiovascular disease (CVD) is a major cause of disability and premature death throughout the world. Diets with antithrombotic components offer a convenient and effective way of preventing and reducing CVD incidence. The ...
Antiplatelet and Antithrombotic Activities of Non-Steroidal Anti-Inflammatory Drugs Containing an N-Acyl Hydrazone Subunit
(Mdpi Ag, 2014-02-01)
Nonsteroidal anti-inflammatory drugs (NSAIDs) 1-5 containing an N-acyl hydrazone subunit were prepared and their antiplatelet and antithrombotic activities assessed in vitro and in vivo. Compounds 1-5 inhibited the platelet ...
Synthesis, antiplatelet and antithrombotic activities of resveratrol derivatives with NO-donor properties
(2017-01-01)
Resveratrol (RVT) is a stilbene with a protective effect on the cardiovascular system; however, drawbacks including low bioavailability and fast metabolism limit its efficacy. In this work we described new resveratrol ...
Antithrombotic and Antioxidant Activity of Amaranth Hydrolysate Obtained by Activation of an Endogenous Protease
(Springer, 2016-06)
Ingestion of diets with antithrombotic and antioxidant components offer a convenient and effective way to prevent and reduce the incidence of cardiovascular diseases. The aim of the present work was to obtain an amaranth ...