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Synthesis and in vitro antiproliferative evaluation of 3-acyl-2-arylamino-1,4-naphthoquinones
(SPRINGER BIRKHAUSER, 2014)
Antiproliferative and structure activity relationships of amaryllidaceae alkaloids
(MDPI, 2015-07-30)
The antiproliferative activity of a set of seven natural Amaryllidaceae alkaloids and 32 derivatives against four cancer cell lines (A2780, SW1573, T47-D and WiDr) was determined. The best antiproliferative activities were ...
SYNTHESIS OF NINE SAFROLE DERIVATIVES AND THEIR ANTIPROLIFERATIVE ACTIVITY TOWARDS HUMAN CANCER CELLS
(Sociedad Chilena de Química, 2010)
Anti-inflammatory and antiproliferative activities of Ixora brevifolia Benth. (Rubiaceae)
(2018-06-03)
The crude extract and fractions from the branches of Ixora brevifolia, a tree found in the Brazilian Cerrado, were tested for anti-inflammatory and in vitro antiproliferative effects. The crude extract and n-hexane fraction ...
Antiproliferative activity of synthetic naphthoquinones related to lapachol. First synthesis of 5-hydroxylapachol
(Pergamon-Elsevier Science Ltd, 2010-04)
A series of 5-hydroxy-1,4-naphthoquinones analogues was synthesized from juglone (6) and their antiproliferative activity against a representative panel of six human solid tumor cell lines has been investigated. The ...
Dimeric Labdane Diterpenes: Synthesis and Antiproliferative Effects
(MDPI AG, POSTFACH, CH-4005 BASEL, SWITZERLAND, 2013)
Antiproliferative activity and p53 upregulation effects of chalcones on human breast cancer cells
(2019-01-01)
Chalcones are valuable structures for drug discovery due to their broad bioactivity spectrum. In this study, we evaluated 20 synthetic chalcones against estrogen-receptor-positive breast cancer cells (MCF-7 line) and ...
Optimization of Eugenia punicifolia (Kunth) D. C. leaf extraction using a simplex centroid design focused on extracting phenolics with antioxidant and antiproliferative activities
(2020-04-27)
Eugenia punicifolia (Kunth) D. C. (Myrtaceae) has been showing interesting biological activities in the literature which was correlated to its phenolic compounds. In the sense of a better recovering of phenolics with the ...
Leaf anatomy of Protium ovatum and its antiproliferative potential in cervical cells
(Soc Brasileira Farmacognosia, 2017-11-01)
The aim of this study was to analyze the morphology and anatomy of the leaves of Protium ovatum Engl., Burseraceae, and verify the antiproliferative activity in cervical cells. For anatomical analysis, the leaf samples ...
Curcumin-cinnamaldehyde hybrids as antiproliferative agents against women’s cancer cells
(2021-01-01)
Curcumin and cinnamaldehyde are natural products whose antineoplastic activity has been well explored in biological evaluations. However, their poor chemical stability under physiological conditions has been an obstacle ...