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Heparins and heparinoids: Occurrence, structure and mechanism of antithrombotic and hemorrhagic activities
(Bentham Science Publ Ltd, 2004-01-01)
The correlation between structure, anticloting, antithrombotic and hemorrhagic activities of heparin, heparan sulfate, low molecular weight heparins and heparin-like compounds from various sources that are in used in ...
Structural features and anticoagulant activities of a novel natural low molecular weight heparin from the shrimp Penaeus brasiliensis
(Elsevier B.V., 1999-08-05)
A natural low molecular weight heparin (8.5 kDa), with an anticoagulant activity of 95 IU/mg by the USP assay, was isolated from the shrimp Penaeus brasiliensis. the crustacean heparin was susceptible to both heparinase ...
Development of new heparin-like compounds and other antithrombotic drugs and their interaction with vascular endothelial cells
(Associação Brasileira de Divulgação Científica, 2001-06-01)
The anticlotting and antithrombotic activities of heparin, heparan sulfate, low molecular weight heparins, heparin and heparin-like compounds from various sources used in clinical practice or under development are briefly ...
Pharmacological characterization of cnidarian extracts from the Caribbean Sea: Evaluation of anti-snake venom and antitumor properties
(2018-08-28)
Background: Cnidarians produce toxins, which are composed of different polypeptides that induce pharmacological effects of biotechnological interest, such as antitumor, antiophidic and anti-clotting activities. This study ...
Naturally-occurring Dimers of Flavonoids as Anticarcinogens
(Bentham Science Publishers, 2013-10)
Biflavonoids are dimers of flavonoid moieties linked by a C-C or C-O-C bond. Simple, complex, rearranged, natural and ketalized Diels-Alder adducts, benzofuran derivatives, and spirobiflavonoids are some of the structural ...
An insight into the sialotranscriptome and virome of Amazonian anophelines
(BioMed Central, 2019)
Background: Saliva of mosquitoes contains anti-platelet, anti-clotting, vasodilatory, anti-complement and antiinflammatory
substances that help the blood feeding process. The salivary polypeptides are at a fast pace ...