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Both XPA and DNA polymerase eta are necessary for the repair of doxorubicin-induced DNA lesions
(ELSEVIER IRELAND LTDCLARE, 2012)
Doxorubicin (DOX) is an important tumor chemotherapeutic agent, acting mainly by genotoxic action. This work focus on cell processes that help cell survival, after DOX-induced DNA damage. In fact, cells deficient for XPA ...
Both XPA and DNA polymerase eta are necessary for the repair of doxorubicin-induced DNA lesions
(Elsevier B.V., 2012-01-01)
Doxorubicin (DOX) is an important tumor chemotherapeutic agent, acting mainly by genotoxic action. This work focus on cell processes that help cell survival, after DOX-induced DNA damage. in fact, cells deficient for XPA ...
Whole-Exome Sequencing Enables Rapid Determination of Xeroderma Pigmentosum Molecular Etiology
(Universidad del Rosario, 2013-06-03)
Xeroderma pigmentosum (XP) is a rare autosomal recessive disorder haracterized by extreme sensitivity to actinic pigmentation changes in the skin and increased incidence of skin cancer. In some cases, patients are affected ...
Gap-filling and bypass at the replication fork are both active mechanisms for tolerance of low-dose ultraviolet-induced DNA damage in the human genome
(Elsevier, 2014-02)
Ultraviolet (UV)-induced DNA damage are removed by nucleotide excision repair (NER) or can be tolerated by specialized translesion synthesis (TLS) polymerases, such as Polη. TLS may act at stalled replication forks or ...
LibreGrowth: A tumor growth code based on reaction-diffusion equations using shared memory
(Elsevier, 2019-10)
In recent years, in-silico experimentation within the field of oncological medicine has been intensively investigated with the aim of better understanding tumor dynamics and dose–response relationships in cancer treatments. ...
A evolução da próclise e o sujeito nulo em peças de teatro brasileiras oitocentistas
(Florianópolis, SC, 2021)
A evolução da próclise e o sujeito nulo em peças de teatro brasileiras oitocentistas
(Florianópolis, SC, 2022)
Estudo fitoquímico e alelopático do extrato de caule de Pterodon emarginatus (Sucupira branca)Phytochemical and allelopathic study of Pterodon emarginatus (Sucupira branco) stem extract
(Universidade Federal de UberlândiaBrasilPrograma de Pós-graduação em Química, 2019)
Elucidação dos mecanismos de integração de minicírculos de kDNA de trypanosoma cruzi no genoma do hospedeiro
(2022-10-03)
A doença de Chagas (DC), infecção tropical causada pelo parasita Trypanosoma cruzi (T.
cruzi), afeta de 6 a 8 milhões de pessoas no mundo. Ainda não existe um tratamento adequado
para a doença na sua forma avançada e a ...