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Papillomavirus: Viral vectors in the gene therapy and new therapeutic targets
(Scholar Science Journals, 2016)
Inhibition of hepatitis C virus using siRNA targeted to the virus and Hsp90
(2017-01-01)
Hepatitis C (HCV) is a viral disease affecting millions of people worldwide, and persistent HCV infection can lead to progressive liver disease with the development of liver cirrhosis and hepatocellular carcinoma. During ...
Advances in the development of entry inhibitors for sialic-acid-targeting viruses
Over the past decades, several antiviral drugs have been developed to treat a range
of infections. Yet the number of treatable viral infections is still limited, and resistance
to current drug regimens is an ever-growing ...
E6AP goes viral: the role of E6AP in viral- and non-viral-related cancers
(Oxford University Press, 2019)
Since its discovery, the E3 ubiquitin ligase E6-associated protein (E6AP) has been studied extensively in two pathological contexts: infection by the human papillomavirus (HPV), and the neurodevelopmental disorder, Angelman ...
Novel therapeutic targets for arenavirus hemorrhagic fevers
(Future Medicine, 2011-01)
Several members of the family Arenaviridae can cause severe hemorrhagic fevers in humans, representing a serious public health problem in endemic areas of Africa and South America. The Lassa virus is the most prevalent and ...
RNA Helicase DDX3: A Double-Edged Sword for Viral Replication and Immune Signaling
(MDPI, 2021)
DDX3 is a cellular ATP-dependent RNA helicase involved in different aspects of RNA metabolism ranging from transcription to translation and therefore, DDX3 participates in the regulation of key cellular processes including ...
Complement System as a Target for Therapies to Control Liver Regeneration/Damage in Acute Liver Failure Induced by Viral Hepatitis
(Hindawi Publishing Corporation, 2019)
Prediction of MicroRNAs in the Epstein–Barr Virus Reveals Potential Targets for the Viral Self-Regulation
(Springer, 2019)
© 2018, Association of Microbiologists of India.Studies involving miRNAs have opened discussions about their broad participation in viral infections. Regarding the Human gammaherpesvirus 4 or Epstein–Barr virus (EBV), ...