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Effects of the BDNF Val66Met polymorphism on anxiety-like behavior following nicotine withdrawal in mice
(Oxford University Press, 2015-12)
Introduction: Nicotine withdrawal is characterized by both affective and cognitive symptoms. Identifying genetic polymorphisms that could affect the symptoms associated with nicotine withdrawal are important in predicting ...
Effects of the brain-derived neurotropic factor variant Val66Met on cortical structure in late childhood and early adolescence
(Pergamon-Elsevier Science Ltd, 2018)
Background: The brain-derived neurotrophic factor (BDNF) Val66Met polymorphism (rs6265) has been associated with several neuropsychiatric disorders and regional structural brain changes in adults, but little is known about ...
Desempenho cognitivo de idosas: estresse precoce, encurtamento telomérico e polimorfismo VAL66MET do BDNF
(Pontifícia Universidade Católica do Rio Grande do SulPorto Alegre, 2014)
Aging is a heterogeneous process resulting of biomarkers elicited by multiple factors, such as adverse environment. A biomarker widely studied as a mediator of aging is the telomeres length. Telomeres are DNA-structures ...
Desempenho cognitivo de idosas: estresse precoce, encurtamento telomérico e polimorfismo VAL66MET do BDNF
(Pontifícia Universidade Católica do Rio Grande do SulPorto Alegre, 2014)
Aging is a heterogeneous process resulting of biomarkers elicited by multiple factors, such as adverse environment. A biomarker widely studied as a mediator of aging is the telomeres length. Telomeres are DNA-structures ...
Avaliação da espessura cortical e volume de estruturas subcorticais associados ao fator neurotrófico derivado do cérebro (BDNF) em uma coorte de alto risco de desenvolvimento de transtornos psiquiátricos durante a infância e adolescência
(Universidade Federal de São Paulo (UNIFESP), 2018-10-22)
Background: The Brain Derived Neurotrophic Factor (BDNF) is a neurotrophin that
plays a key role in synaptic plasticity and transmission. The BDNF Val66Met
polymorphism (rs6265) has been associated with neuropsychiatric ...
Neuronal Correlates of Brain-derived Neurotrophic Factor Val66Met Polymorphism and Morphometric Abnormalities in Bipolar Disorder
(NATURE PUBLISHING GROUP, 2009)
The brain-derived neurotrophic factor (BDNF) Val66Met polymorphism has been proposed as a possible candidate for involvement in the pathophysiology of bipolar disorder ( BD). To determine whether an association exists ...
Growth factors and hormones pro-peptides: the unexpected adventures of the BDNF prodomain
(Wiley Blackwell Publishing, Inc, 2017-05)
Most growth factors and hormones are synthesized as pre-pro-proteins which are processed to the biologically active mature protein. The pre- and prodomains are cleaved from the precursor protein in the secretory pathway ...
Relação do polimorfismo BDNF val66met e níveis periféricos de BDNF com a doença de Parkinson e sua sintomatologia
(Universidade Federal do Rio Grande do NorteBrasilUFRNPROGRAMA DE PÓS-GRADUAÇÃO EM PSICOBIOLOGIA, 2015-05-12)
Neurodegenerative diseases are frequently studied due to the increasing
number of cases associated with the populational ageing and to the impact on
the conditions on the quality of life. Parkinson’s disease (DP) is the ...