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Amantadine as a drug to mitigate the effects of COVID-19
The SARS-CoV-2 virus has spread around the world. At this time, there is no vaccine that can help people prevent
the spread of coronavirus.
We are proposing amantadine as a drug that can be used to mitigate the effects ...
Structure and functional dynamics characterization of the ion channel of the human respiratory syncytial virus (hRSV) small hydrophobic protein (SH) transmembrane domain by combining molecular dynamics with excited normal modes
(Springer, 2016-12-01)
The human respiratory syncytial virus (hRSV) is the major cause of lower respiratory tract infection in children and elderly people worldwide. Its genome encodes 11 proteins including SH protein, whose functions are not ...
Structural biology of coronavirus ion channels
(International Union of Crystallography, 2021-04)
Viral infection compromises specific organelles of the cell and readdresses its functional resources to satisfy the needs of the invading body. Around 70% of the coronavirus positive-sense single-stranded RNA encodes ...
Estudo por dinâmica molecular e ressonância magnética nuclear de Viroporinas: análise da estrutura e do mecanismo de portão da proteína SH (HRSV) e da proteína M2 (vírus Influenza)
(Universidade Estadual Paulista (Unesp), 2018-01-29)
As proteínas SH do HRSV e M2 do IAV são membros das viroporinas, uma família de proteínas virais pequenas de membrana. A proteína SH tem 64 resíduos de aminoácidos e uma estrutura pentamérica composta por alfa-hélice ...
Host-membrane interacting interface of the SARS coronavirus envelope protein: Immense functional potential of C-terminal domain
he Envelope (E) protein in SARS Coronavirus (CoV) is a small structural protein, incorporated as part of
the envelope. A major fraction of the protein has been known to be associated with the host membranes,
particularly ...
Almendravirus : A Proposed New Genus of Rhabdoviruses Isolated from Mosquitoes in Tropical Regions of the Americas
(American Society of Tropical Medicine and HygienePrograma de Estudio y Control de Enfermedades Tropicales (PECET)Baltimore, Estados Unidos, 2021)
Posibles uniones entre proteínas relacionadas con la vía PPARγ – NFκB y proteínas no estructurales de rotavirus
(Universidad Nacional de ColombiaBogotá - Ciencias - Doctorado en BiotecnologíaInstituto de Biotecnología (IBUN)Facultad de CienciasBogotá, ColombiaUniversidad Nacional de Colombia - Sede Bogotá, 2019)
Rotavirus es un virus perteneciente a la familia Reoviridae, icosaédrico sin envoltura; su cápside está constituida por tres capas: externa, media e interna. Mide aproximadamente 70 nm de diámetro, su genoma de 11 segmentos ...