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Bone metabolism dysfunction mediated by the increase of proinflammatory cytokines in chronic HIV infection
(2017-03-01)
Despite the efficacy of antiretroviral therapy (ART) on the control of viral replication, the current challenge is to decrease the chronic inflammatory status and toxicity of the antiretroviral drugs that contribute to ...
Effect of melatonin on bone metabolism in ovariectomized rats
(Pergamon-Elsevier Science Ltd, 2001-07)
To asses the effect of pharmacological dose of melatonin on bone metabolism in ovariectomized rats, urinary deoxypyridinoline (a marker of bone resorption) and calcium excretion, circulating levels of calcium, phosphorus ...
Olpadronate prevents the bone loss induced by cyclosporine in the rat
(Springer, 2002-01)
The aim of the present in vivo experimental study was to investigate changes in bone turnover and bone mineral density (BMD) induced by cyclosporine (CsA) administration. The effectiveness of olpadronate (OPD) in preventing ...
Bone loss in hepatitis B virus-infected patients can be associated with greater osteoclastic activity independently of the retroviral use
(2021-12-01)
Nucleoside/nucleotide analogs such as tenofovir, have been used as long-term therapy for the treatment of hepatitis B and side effects such as the reduction in bone mineral density have been associated with their use. To ...
Effect of hormone replacement therapy on the bone mass and urinary excretion of pyridinium cross-links
(Associação Paulista de Medicina - APM, 2000-01-06)
CONTEXT: The menopause accelerates bone loss and is associated with an increased bone turnover. Bone formation may be evaluated by several biochemical markers. However, the establishment of an accurate marker for bone ...
Long-term evaluation of alendronate treatment on the healing of calvaria bone defects in rats. Biochemical, histological and immunohistochemical analyses
(2020-09-01)
Objective: The aim of this study was to investigate the effects of the long-term alendronate administration on bone healing in defects created in rat calvarias. Materials and methods: Female Wistar rats were randomly ...
Avaliação dos efeitos do tenofovir na densidade mineral óssea de pacientes com hepatite B crônica não infectados pelo HIV
(Universidade Estadual Paulista (Unesp), 2019-07-04)
A hepatite B é um importante problema de saúde pública mundial e se associa a consideráveis taxas de mortalidade. As medicações de uso oral para o tratamento da hepatite B, denominados em conjunto de análogos de ...
Relation between probiotic milk administration and some bone turnover markers
(Medwell Publishing, 2005-12)
The evaluation of several biochemical markers can reflect the overall skeletal rate of bone turnover. Scarce information about the effects of probiotic foods on the calcium metabolism and bone turnover markers is available. ...
Severe magnesium deficiency compromises systemic bone mineral density and aggravates inflammatory bone resorption
(2020-03-01)
We sought to evaluate the effects of magnesium (Mg) intake deficiency on bone metabolism in rats with induced periodontal disease (PD). Holtzman rats were randomly divided into two groups: Control — animals fed a standard ...
Influência dos marcadores inflamatórios no metabolismo ósseo de pacientes infectados pelo HIV em uso ou não da terapia antirretroviral
(Universidade Estadual Paulista (Unesp), 2017-02-24)
A história natural da infecção pelo HIV e a terapia antirretroviral (TARV) já estão bem esclarecidos, por proporcionarem aumento da contagem das células T CD4+, redução da viremia e diminuição de riscos para doenças ...