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Tumor suppressor in lung cancer-1 (TSLC1) functions as a glioma tumor suppressor
(Lippincott Williams, 2006)
Inactivation of tumor suppressor gene pten in early and advanced gallbladder cancer
(Biomed Central Ltd., 2015)
BACKGROUND:
PTEN is a tumor suppressor gene that regulates the PTEN/PI3k/AKT/mTOR pathway, which is frequently altered in human cancers including gallbladder cancer (GBC). To determine the frequency of PTEN expression in ...
Inactivation of tumor suppressor gene pten in early and advanced gallbladder cancer
(Biomed Central Ltd., 2015)
BACKGROUND:
PTEN is a tumor suppressor gene that regulates the PTEN/PI3k/AKT/mTOR pathway, which is frequently altered in human cancers including gallbladder cancer (GBC). To determine the frequency of PTEN expression in ...
Caveolae and caveolae-like membrane domains in cellular signaling and disease: Identification of downstream targets for the tumor suppressor protein caveolin-1
(Society of Biology of Chile, 2002)
Caveolae are small, flask-shaped invaginations of the plasma membrane present on a large number of mammalian cells. Recent results obtained with knock-out mice for the gene caveolin-1 demonstrate that expression of caveolin-1 ...
Identification of a putative nuclear localization signal in the tumor suppressor maspin sheds light on its nuclear import regulation
(2019-07-01)
The tumor suppressor activity of maspin (mammary serine protease inhibitor) has been associated with its nuclear localization. In this study we explore the regulation of maspin nuclear translocation. An in vitro nuclear ...
Silencing of tumor suppressor genes RASSF1A, SLIT2, and WIF1 by promoter hypermethylation in hereditary breast cancer
(2013)
Promoter hypermethylation is gaining strength as one of the main mechanisms through which tumor suppressor genes are silenced during tumor progression. Three tumor suppressor genes are frequently found methylated in their ...
MicroRNA-100 Acts as a Tumor Suppressor in Human Bladder Carcinoma 5637 Cells
(Asian Pacific Organization Cancer Prevention, 2011-01-01)
Bladder carcinoma is one of the most common tumors in the world and, despite the therapy currently available, most of the patients relapse. Better understanding of the factors involved in disease pathogenesis would provide ...
MicroRNA-100 Acts as a Tumor Suppressor in Human Bladder Carcinoma 5637 Cells
(Asian Pacific Organization Cancer Prevention, 2011-01-01)
Bladder carcinoma is one of the most common tumors in the world and, despite the therapy currently available, most of the patients relapse. Better understanding of the factors involved in disease pathogenesis would provide ...
MicroRNA-100 acts as a tumor suppressor in human bladder carcinoma 5637 cells
(2011-01-01)
Bladder carcinoma is one of the most common tumors in the world and, despite the therapy currently available, most of the patients relapse. Better understanding of the factors involved in disease pathogenesis would provide ...