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Sonographic appearance of gestational trophoblastic disease evolving into epithelioid trophoblastic tumor
(JOHN WILEY & SONS LTD, 2010)
Epithelioid trophoblastic tumor is a distinctive but rare trophoblastic tumor. It derives from intermediate trophoblastic cells of the chorion laeve and is usually associated with a previous gestational event. We report ...
Interplay between neutrophils and trophoblast cells conditions trophoblast function and triggers vascular transformation signals
(Wiley-liss, Div John Wiley & Sons Inc, 2019-09-26)
Normal placentation entails highly regulated interactions of maternal leukocytes with vascular and trophoblast cells to favor vascular transformation. Neutrophil activation and neutrophil extracellular trap (NET) formation ...
Trophoblast cells primed with vasoactive intestinal peptide enhance monocyte migration and apoptotic cell clearance through αvβ3 integrin portal formation in a model of maternal-placental interaction
(Oxford University Press, 2015-05)
STUDY HYPOTHESIS: Is apoptotic cell phagocytosis by monocytes modulated by pathways elicited by vasoactive intestinal peptide (VIP) action on trophoblast? STUDY FINDING: Targeting trophoblast cells with VIP induces monocyte ...
Laminin promotes in vitro outgrowth of mouse trophoblast from blastocysts cultured in hanging drop
(1997)
Differentiation of the nonadherent trophectoderm cells of the mammalian embryo into attachment-competent trophoblast cells appears to be a necessary event for invasion of the uterine stroma. We have used a hanging drop ...
Trophoblast cells inhibit neutrophil extracellular trap formation and enhance apoptosis through vasoactive intestinal peptide-mediated pathways
(Oxford University Press, 2016-12)
STUDY QUESTION:Do human trophoblast cells modulate neutrophil extracellular trap (NET) formation, reactive oxygen species (ROS) synthesis and neutrophil apoptosis through mechanisms involving vasoactive intestinal peptide ...
Vasoactive Intestinal Peptide modulates trophoblast-derived cell line function and interaction with phagocytic cells through autocrine pathways
(Nature Publishing Group, 2016-05)
Trophoblast cells migrate and invade the decidual stroma in a tightly regulated process to maintain immune homeostasis at the maternal-placental interface during the first weeks of pregnancy. Locally synthesized factors ...
Placentation in the degu (Octodon degus): Analogies with extrasubplacental trophoblast and human extravillous trophoblast
(2007)
This study examined the placentation in the degu, the origin of the extrasubplacental trophoblast (EST) (extravillous trophoblast in human), and the activity of Na+/K+ ATPase in the placental barrier during different ...
Apoptotic index for prediction of postmolar gestational trophoblastic neoplasia
(Elsevier B.V., 2016-09-01)
BACKGROUND: Although 85% of patients with a complete hydatidiform mole achieve spontaneous remission after a few months, 15% of them will experience gestational trophoblastic neoplasia, which requires chemotherapy. To date, ...