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Herbal extracts differentially inhibit oxidative effects caused by the biotransformation of nifurtimox, nitrofurantoin and acetaminophen on rat liver microsomes
(Universidad de Santiago de Chile, 2017)
Inflammation is a cellular defensive mechanism associated to oxidative stress. The administration of nitrofurantoin, nifurtimox and acetaminophen generates oxidative stress by their biotransformation through CYP450 system. ...
The thiol-specific antioxidant enzyme prevents mitochondrial permeability transition - Evidence for the participation of reactive oxygen species in this mechanism
(Amer Soc Biochemistry Molecular Biology IncBethesdaEUA, 1998)
Cytosolic thioredoxin peroxidase I is essential for the antioxidant defense of yeast with dysfunctional mitochondria
(Elsevier Science BvAmsterdamHolanda, 2001)
Specific effects of reactive thiol drugs on mitochondrial bioenergetics
(Springer, 2011-02-01)
In this minireview, the more recent findings about the effects of peculiar reactive thiol drugs on mitochondria are presented. These include the following compounds: metallo meso-tetrakis porphyrins, palladacycles, telluranes ...
Transsulfuration is an active pathway for cysteine biosynthesis in Trypanosoma rangeli
(BioMed Central, 2015)
On the mechanisms of phenothiazine-induced mitochondrial permeability transition: Thiol oxidation, strict Ca(2+) dependence, and cyt c release
(PERGAMON-ELSEVIER SCIENCE LTD, 2010)
Phenothiazines (PTZ) are drugs widely used in the treatment of schizophrenia. Trifluoperazine, a piperazinic PTZ derivative, has been described as inhibitor of the mitochondrial permeability transition (MPT). We reported ...
Yeast oxidative stress response - Influences of cytosolic thioredoxin peroxidase I and of the mitochondrial functional state
(Blackwell PublishingOxfordInglaterra, 2006)
Regulation of mitochondrial thioredoxin peroxidase I expression by two different pathways: One dependent on cAMP and the other on heme
(Pergamon-elsevier Science LtdOxfordInglaterra, 2002)