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Why do we still have not a vaccine against chagas disease?
(Fundação Oswaldo Cruz / IOC, 2022)
Current development of COVID-19 diagnostics, vaccines and therapeutics
A novel coronavirus, designated as SARS-CoV-2, first emerged in Wuhan City, Hubei Province, China, in
late December 2019. The rapidly increasing number of cases has caused worldwide panic. In this review,
we describe ...
Inoculation site from a cutaneous melanoma patient treated with an allogeneic therapeutic vaccine: A case report
(Frontiers Media S.A., 2015-04)
We have developed a therapeutic vaccine consisting of a mixture of lethally-irradiated allogeneic cutaneous melanoma cell lines with BCG and GM-CSF as adjuvants. The CSF-470 vaccine is currently being assayed in a Phase ...
Vaccine design against chagas disease focused on the use of nucleic acids
(MDPI, 2022)
Chagas disease is caused by the protozoan Trypanosoma cruzi and is endemic to Central and South America. However, it has spread around the world and affects several million people. Treatment with currently available drugs ...
Prospect of SARS-CoV-2 spike protein: Potential role in vaccine and therapeutic development
The recent outbreak of the betacoronavirus SARS-CoV-2 has become a significant
concern to public health care worldwide. As of August 19, 2020, more than 22,140,472 people
are infected, and over 781,135 people have died ...
Vaccination-induced skin-resident memory CD8(+) T cells mediate strong protection against cutaneous melanoma
(Taylor & Francis, 2018)
Memory CD8(+) T cell responses have the potential to mediate long-lasting protection against cancers. Resident memory CD8(+) T (Trm) cells stably reside in non-lymphoid tissues and mediate superior innate and adaptive ...
Chronic Chagas disease: Can prophylaxis and therapeutic vaccines crack this "hard nut"?
(Future Medicine, 2016-02)
Although, none of the therapeutic vaccines assessed so far have reached sterilizing immunity, the results obtained in terms of disease control indicate that immune intervention might be used for therapeutic purposes.
Recent advances in DNA vaccines for autoimmune diseases
(Expert Reviews, 2009-02-01)
Vaccination is one of the most powerful health tools available owing to its ability to confer protection against various diseases. The long-term impact of such protection in terms of public-health savings is nearly ...
Recent advances in DNA vaccines for autoimmune diseases
(Expert Reviews, 2009-02-01)
Vaccination is one of the most powerful health tools available owing to its ability to confer protection against various diseases. The long-term impact of such protection in terms of public-health savings is nearly ...