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Pioneer factors and ATP-dependent chromatin remodeling factors interact dynamically: A new perspective: Multiple transcription factors can effect chromatin pioneer functions through dynamic interactions with ATP-dependent chromatin remodeling factors
(John Wiley & Sons Inc, 2016-11)
Transcription factor (TF) signaling regulates gene transcription and requires a complex network of proteins. This network includes co-activators, co-repressors, multiple TFs, histone-modifying complexes, and the basal ...
A Genome-wide Screen for Neurospora crassa Transcription Factors Regulating Glycogen Metabolism
(Amer Soc Biochemistry Molecular Biology Inc, 2011-11-01)
Transcription factors play a key role in transcription regulation as they recognize and directly bind to defined sites in promoter regions of target genes, and thus modulate differential expression. The overall process is ...
Quantifying transcription factor binding dynamics at the single-molecule level in live cells
(Academic Press Inc Elsevier Science, 2017-07)
Progressive, technological achievements in the quantitative fluorescence microscopy field are allowing researches from many different areas to start unraveling the dynamic intricacies of biological processes inside living ...
Reconstruction of regulatory network predicts transcription factors driving the dynamics of zebrafish heart regeneration
(2022-04-20)
The limited regenerative capacity in mammals has serious implications for cardiac tissue damage. Meanwhile, zebrafish has a high regenerative capacity, but the regulation of the heart healing process has yet to be elucidated. ...
Imaging transcription factors dynamics with advanced fluorescence microscopy methods
(Elsevier Science, 2018-12)
Pluripotent stem cells (PSCs) are capable of self-renewing and producing all cell types derived from the three germ layers in response to developmental cues, constituting an important promise for regenerative medicine. ...
Dynamical reorganization of the pluripotency transcription factors Oct4 and Sox2 during early differentiation of embryonic stem cells
(Nature, 2020-03)
Pluripotency maintenance requires transcription factors (TFs) that induce genes necessary to preserve the undifferentiated state and repress others involved in differentiation. Recent observations support that the heterogeneous ...
Emerging roles of ATF2 and the dynamic AP1 network in cancer
(Nature Publishing Group, 2010-01)
Cooperation among transcription factors is central for their ability to execute specific transcriptional programmes. The AP1 complex exemplifies a network of transcription factors that function in unison under normal ...
A Genome-wide Screen for Neurospora crassa Transcription Factors Regulating Glycogen Metabolism
(Amer Soc Biochemistry Molecular Biology Inc, 2011-11-01)
Transcription factors play a key role in transcription regulation as they recognize and directly bind to defined sites in promoter regions of target genes, and thus modulate differential expression. The overall process is ...
Transcriptional Bursting and Co-bursting Regulation by Steroid Hormone Release Pattern and Transcription Factor Mobility
(Cell Press, 2019-09-19)
Genes are transcribed in a discontinuous pattern referred to as RNA bursting, but the mechanisms regulating this process are unclear. Although many physiological signals, including glucocorticoid hormones, are pulsatile, ...
Transcriptional memory and switching in the Plasmodium falciparum rif gene family
(ELSEVIER SCIENCE BV, 2009)
The human malaria parasite Plasmodium falciparum expresses erythrocyte-surface directed variant antigens which are important virulence factors Many are transcribed from multigene families and presumably their mode of ...