Artículos de revistas
Emerging roles of ATF2 and the dynamic AP1 network in cancer
Fecha
2010-01Registro en:
Lopez Bergami, Pablo Roberto; Lau, Eric ; Ronai, Zeev ; Emerging roles of ATF2 and the dynamic AP1 network in cancer; Nature Publishing Group; Nature Reviews Cancer; 10; 1-2010; 65-76
1474-175X
1474-1768
Autor
Lopez Bergami, Pablo Roberto
Lau, Eric
Ronai, Zeev
Resumen
Cooperation among transcription factors is central for their ability to execute specific transcriptional programmes. The AP1 complex exemplifies a network of transcription factors that function in unison under normal circumstances and during the course of tumour development and progression. This Perspective summarizes our current understanding of the changes in members of the AP1 complex and the role of ATF2 as part of this complex in tumorigenesis.